JCEG ID |
JCEG193 |
Name |
gly-18
WormBase
NCBI Gene
|
Human Ortholog |
GGDB:GCNT3
OMIM:
OrthoList :
GCNT7
GCNT4
GCNT2
GCNT3
GCNT1
GCNT6
(Ensembl Compara)
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
|
Family Name |
b6GnT |
Locus Tag |
F22D6.11
|
RNAi phenotype |
phenotype
|
WT
|
Microscope observation (Image)
|
|
COPAS (Image)
|
Normal
|
hsp-4::GFP (Image)
|
|
|
Sequence Features |
kr:Detected
tm:soluble
dxd:GVD/DEG
gg_motif:M1, M2, M3, M4, M5
|
Sequence |
CDS
atggtacgattaaaaggcacaattcctagtcttgttacatatgctgcact tgttatttttctttacttattcattgttaaaccattagttccaagaatat tggaaagcctaaattcatctcgaaacccgcaggaaacgagcattttgtca aagatcgagaatgacttgcttgatgatctggatattaattgcttgaatat ttttaatggttccaagaatagaaatcaattacgcatagttaattcaagaa gtatagaagataaattgctgtactcaaccgatagatgccaaacgctgaaa tctctattccgattcaataaagtaccgctatcaccagaagaagaaagttt tccattgtcatatggacttctcgtatacaaggaattatcacaggttctat tcatgctctcatcaatttatcatcctcaaaacgaatactgtattgcagtt ggcgaaaattcagctccaatttttcaaaatttgctcaaagagctctcaaa ttgcttttcaaatattcattttatgaaacgaccgccgattgattggggaa gccacgaaataataaattcagcatatgattgtctggaatttctgagtcac ttgaaatccgattggagatattttcaatatttatcaggagttgatattcc attaaagacaaatcttgaaatggttcaaatattgaaacatctgaatggaa ctgcaaatgtcgaaatcaaaccatatcaatatcaacgccttcgaggtaaa aatgagactcagtctccactgccgctttttaagtcatcactgtcatcact aataccaagagaagctgccaatcacttatcatcatcaagcattcctcaac aactattggaatttcttcgaaatactggaattgctgatgaaggattttgg ggaactctttttggaaacaagaacttgtttgatattcctggatctttgaa tttcaaagaatggatatcatacaaaaataatgtagaaacgaacttaacat atcccactgatggatggagatattatatatccagagatcaaatatggtca aagcccaattgtcataattacatgaaagctgggtcatgtgtttttggaat tggagatgtcccaagattattgaagtcaaaagcgttggttgctcataaat tttacctaaaatcagagccagaagcatatttttgtttattaaaggaacac cgtcgccgaacgtgtaatcccgatttaacatttgatgcatcaaaatactc agagttaccgcaagttgaactatcacgaggtcttgccatgccacaactga cacataaaaattggattttatga
|
Protein
MVRLKGTIPSLVTYAALVIFLYLFIVKPLVPRILESLNSSRNPQETSILSKIENDLLDDL DINCLNIFNGSKNRNQLRIVNSRSIEDKLLYSTDRCQTLKSLFRFNKVPLSPEEESFPLS YGLLVYKELSQVLFMLSSIYHPQNEYCIAVGENSAPIFQNLLKELSNCFSNIHFMKRPPI DWGSHEIINSAYDCLEFLSHLKSDWRYFQYLSGVDIPLKTNLEMVQILKHLNGTANVEIK PYQYQRLRGKNETQSPLPLFKSSLSSLIPREAANHLSSSSIPQQLLEFLRNTGIADEGFW GTLFGNKNLFDIPGSLNFKEWISYKNNVETNLTYPTDGWRYYISRDQIWSKPNCHNYMKA GSCVFGIGDVPRLLKSKALVAHKFYLKSEPEAYFCLLKEHRRRTCNPDLTFDASKYSELP QVELSRGLAMPQLTHKNWIL
|
References |
Warren CE, Krizus A, Dennis JW
Glycobiology
(2001)
11
(11)
:979-88
[PMID : 11744632]
Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues.
Berninsone PM
WormBook
(2006)
:1-22
[PMID : 18050430]
Carbohydrates and glycosylation.
Shaye DD, Greenwald I
PLoS ONE
(2011)
6
(5)
:e20085
[PMID : 21647448]
OrthoList: a compendium of C. elegans genes with human orthologs.
|
Functional Descriptions |
gly-18
GLY-18 is similar to 2/I N-acetylglucosaminyltransferase.
|
Deletion Mutants |
qa704
|
In Situ |
|
Expression |
Expression
db_name |
wbbt |
name |
def |
reliability |
expr_pattern |
paper |
WormAtlas |
WB |
WBbt:0003675
|
muscle cell |
"contractile cell that makes up muscle tissue." [WB:rynl] |
Enriched |
WBPaper00031003 : 0hr_muscle_enriched, total_muscle_enriched
|
WBPaper00031003
|
WormAtlas
|
WB |
WBbt:0003955
|
ALA |
"Neuron class of one neuron, sends processes laterally and along dorsal cord." [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0004506
|
gon_herm_dtc_P |
"Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
|
WB |
WBbt:0004520
|
gon_herm_dtc_A |
"Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
|
WB |
WBbt:0004783
|
GLRR |
"Set of six cells that form a thin cylindrical sheet between pharynx and ring neuropile; no chemical synapses, but gap junctions with muscle arms and RME motor neurons" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0004784
|
GLRL |
"Set of six cells that form a thin cylindrical sheet between pharynx and ring neuropile; no chemical synapses, but gap junctions with muscle arms and RME motor neurons" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0004849
|
vm1 |
"Vulval muscle 1" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
|
WB |
WBbt:0004850
|
vm1 |
"Vulval muscle 1" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0004853
|
vm1 |
"Vulval muscle 1" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
|
WB |
WBbt:0004854
|
vm1 |
"Vulval muscle 1" [ISBN:0-87969-307-X] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
|
WB |
WBbt:0005750
|
socket cell |
"An interfacial epithelial cell which forms a distal cap on a sheath cell to bind the sheath of a sensillum to the neighboring hypodermis, via adherens junctions. There is often a narrow opening through the socket from the exterior into the sheath channel, allowing ciliated dendrites to be exposed to the external environment. The socket cell functions similarly to a glial cell." [WBPaper:00038216] |
Partial |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0005751
|
coelomocyte |
"A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles." [WBPaper:00038216] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0005751
|
coelomocyte |
"A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles." [WBPaper:00038216] |
Enriched |
WBPaper00037950 : coelomocytes_embryo_SelectivelyEnriched, coelomocytes_embryo_enriched
|
WBPaper00037950
|
WormAtlas
|
WB |
WBbt:0005753
|
seam cell |
"a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail" [WB:rynl, WBPaper:00038216] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0005772
|
intestine |
"A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] |
Enriched |
WBPaper00040985 : AIN-2_L4_intestine
|
WBPaper00040985
|
WormAtlas
|
WB |
WBbt:0005784
|
germ line |
"cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes." [ISBN:0140512888] |
Enriched |
WBPaper00044760 : germline_specific
|
WBPaper00044760
|
|
WB |
WBbt:0005796
|
intestinal muscle |
"intestinal muscle cell, attach to intestine and body wall anterior to anus" [WB:Paper00000653] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0005798
|
anal sphincter muscle |
"a saddle-shaped muscle cell that encircles the intestinal-rectal valve" [WB:rynl, WBPaper:00038216] |
Certain |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
WB |
WBbt:0005813
|
body wall musculature |
"Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion." [ISBN:0-87969-433-5] |
Partial |
WB:Expr1786
|
WBPaper00005030
|
WormAtlas
|
|
WBGene00001643
Phenotype
Homology_paralog
|
|
Phenotype |
Definition |
RNAi / Allele |
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|