| JCEG ID |
Family |
Name |
Locus Tag |
Human Ortholog Name |
OMIM |
GWAS Catalog |
|
|
JCEG006
*
=
|
Asparagine-linked glycosylation (ALG) genes |
|
C08B11.8 |
ALG6
|
603147
604566
|
|
|
|
JCEG015
*
=
|
Asparagine-linked glycosylation (ALG) genes |
algn-14 |
M02B7.4 |
ALG14
|
612866
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| UPSTREAM |
|
0.00000005
(proportions)
|
|
0.7
(% increase)
|
[NR] |
22359512
|
|
Demirkan A 2012-02-16 PLoS Genet
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
|
| MAPPED |
0.49 |
0.000000000000000002
|
|
0.1651
(unit decrease)
|
[0.128-0.202] |
23362303
|
|
Wu JH 2013-01-29 Circ Cardiovasc Genet
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
| MAPPED |
0.451 |
0.00000000003
|
|
0.178
(unit incease)
|
[0.125-0.23] |
23362303
|
|
Wu JH 2013-01-29 Circ Cardiovasc Genet
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
|
|
|
JCEG049
*
=
|
Fucosyltransferases |
fut-3 |
F59E12.13 |
FUT5 FUT1 FUT10 FUT11
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.0000000003
|
|
|
|
24941225
|
|
Liang Y 2014-06-18 PLoS One
Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
|
|
|
|
JCEG069
*
=
|
GPI-anchor synthesis |
|
B0491.1 |
PIGM
|
610273
610293
|
|
|
|
JCEG071
*
=
|
GPI-anchor synthesis |
|
C27A12.9 |
PIGO
|
614730
614749
|
|
|
|
JCEG075
*
=
|
GPI-anchor synthesis |
|
F17C11.7 |
PIGT
|
610272
615398
615399
|
|
|
|
JCEG059
*
=
|
GPI-anchor synthesis |
hpo-3 |
F33D11.9 |
GPAA1
|
603048
|
|
|
|
JCEG081
*
=
|
GlcNAcT(GnT) |
gly-14 |
M01F1.1 |
MGAT1
|
160995
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.85 |
0.000006
(females)
|
|
0.16
(kg decrease)
|
[NR] |
19851299
|
|
Johansson A 2009-10-22 Obesity (Silver Spring)
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
|
| DOWNSTREAM |
0.85 |
0.00000007
(females)
|
|
2.96
(kg decrease)
|
[NR] |
19851299
|
|
Johansson A 2009-10-22 Obesity (Silver Spring)
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
|
| MAPPED |
0.47 |
0.000005
(HDL-C)
|
|
0.23
(mg/dL increase)
|
[NR] |
19197348
|
|
Lowe JK 2009-02-06 PLoS Genet
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
|
| DOWNSTREAM |
0.14 |
0.000008
(EA-glucose response)
|
|
3.67
(mg/dL increase)
|
[2.06-5.28] |
23400010
|
|
Del-Aguila JL 2013-02-12 Pharmacogenomics J
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
|
|
|
|
JCEG090
*
=
|
GlcT |
cgt-3 |
F59G1.1 |
UGCG
|
602874
|
|
|
|
JCEG120
|
Glyco_transf_92 |
|
F46F5.7 |
|
|
|
|
|
JCEG126
*
=
|
Glycosaminoglycan (GAG ) and Chitin synthesis genes |
mig-22 |
PAR2.4 |
CHPF
|
608037
610405
|
|
|
|
JCEG161
*
=
|
Sulfotransferase and sulfation-related genes |
hst-1 |
F08B4.6 |
NDST1
|
600853
603268
603950
615039
|
|
|
|
JCEG164
*
=
|
UGCGL1 |
uggt-2 |
F26H9.8 |
UGGT1
|
605897
605898
|
|
|
|
JCEG165
*
=
|
UGCGL1 |
uggt-1 |
F48E3.3 |
UGGT1 UGGT2
|
605897
605898
|
|
|
|
JCEG171
*
=
|
b3GalT1/b3GnT orthologs |
|
C47F8.6 |
B3GALT1
|
603095
604066
605863
615313
615315
615357
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
0.103 |
0.000002
(Amylin )
|
|
0.03
(pM increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| MAPPED |
0.083 |
0.000008
(Diet fat )
|
|
0.04
(%energy increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| DOWNSTREAM |
0.04 |
0.000000002
(KvDMR 21)
|
|
|
|
23725790
|
|
Renteria ME 2013-06-03 Twin Res Hum Genet
GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.
|
|
|
|
JCEG187
*
=
|
b4GalT |
sqv-3 |
R10E11.4 |
B4GALT7
|
130070
137060
604013
604014
604015
607091
|
|
|
|
JCEG193
*
=
|
b6GnT |
gly-18 |
F22D6.11 |
GCNT3
|
|
|
|
|
JCEG203
*
=
|
b6GnT |
|
F30A10.4 |
GCNT4
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.000004
|
0.0888
|
|
(unit increase)] |
23362303
|
|
Wu JH 2013-01-29 Circ Cardiovasc Genet
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
|
|
|
JCEG197
*
=
|
b6GnT |
|
R07C3.3 |
GCNT3
|
|
|
|
|
JCEG210
*
=
|
iGnT orthologs |
|
F21H7.10 |
GCNT2
|
|
|
|
|
JCEG211
*
=
|
iGnT orthologs |
|
C18G1.3 |
GCNT2
|
|
|
|
|
JCEG215
*
=
|
iGnT orthologs |
|
F56H6.6 |
GCNT2
|
|
|
|