JCGG-STR027271:JCGGDB ID

JCGGDB Glycan Structure Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)

Glycan Information

Glyco Tree get Image

Composition

Hex 3 HexNAc 1 Neu5Ac 1
Mass Value Search

Gal 2 GalNAc 1 Glc 1 Neu5Ac 1
Structural Isomer Search

Descriptors Computed from Structure

InChIKey	ARFQJPSHMFTBIY-BQBUPSDLSA-N
InChI	InChI=1S/C37H62N2O29/c1-9(45)38-17-11(47)3-37(36(58)59,67-30(17)19(49)12(48)4-40)68-31-21(51)14(6-42)62-35(26(31)56)66-29-18(39-10(2)46)33(61-13(5-41)20(29)50)64-28-16(8-44)63-34(25(55)23(28)53)65-27-15(7-43)60-32(57)24(54)22(27)52/h11-35,40-44,47-57H,3-8H2,1-2H3,(H,38,45)(H,39,46)(H,58,59)/t11-,12+,13+,14+,15+,16+,17+,18+,19+,20-,21-,22+,23+,24+,25+,26+,27+,28-,29+,30+,31-,32+,33-,34-,35-,37-/m0/s
SMILES	CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]4[C@@H](CO)O[C@@H](O[C@@H]5[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@@H]3NC(C)=O)[C@@H]2O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

Mass

	Monoisotopic Mass	Average Mass
Underivatised Oligosaccharides	998.3437	998.8953
Permethylated Oligosaccharides	1264.6414	1265.4059
Peracetylated Oligosaccharides	1670.5128	1671.4916

Glycan Motifs

Motif ID	Structure / SubStructure Name	Note
JCGG-MOTIF3003	ganglio	Reducing Terminal
JCGG-MOTIF4038	GM1b
JCGG-MOTIF4114	Neu5Ac(a2-3)Gal(b1)	NON-Reducing Terminal

ID History Deleted Version

JCGG-STR031354(2)

External Links

GlycoEpitope (Antiglycan Antibody)

GlycoEpitope GLPD-000039 GLPD-000039

Name:   GM1b
Description:   IV³Neu5Ac Gg₄Cer
Reducing terminal:   (b-1)Cer

GMDB (MSⁿ)

GMDB OLG-000202

JCGG	JCGG JGD-000482 JGD-000482 Reducing terminal: (b-1)Cer

LipidBank (Spectral Data)

LipidBank GSG1295 GSG1295

Description: NeuAca2-3Galb1-3GalNAcb1-4Galb1-4Glcb1-1Cer
Reducing terminal: (b-)Cer

GlycomeDB (Structure)

GlycomeDB 622 622

KEGG (Structure)

KEGG G00125 G00125

PACDB(Pathogen adhesion)

Pathogen:	Influenza virus (A/PR/8/34; H1N1; human)
Glycan Name:	GM1b [ Binding]

Pathogen:	Influenza virus (B/Lee/40; human)
Glycan Name:	GM1b [ Binding]

Pathogen:	Influenza virus (C/Ann Arbor/1/50; human)
Glycan Name:	GM1b [ Not Binding]

CarbBank

CCSD : 771

Title : Further characterization of the structure of GM1b ganglioside from rat ascites hepatoma

Authors : Matsumoto M; Taki T; Samuelsson B; Pascher I; Hirabayashi Y; Li SC; Li YT

Info : J Biol Chem (1981) 256: 9737-9741

TAXID : 10116 Other Data : ascites hepatoma Other Data : 2010-12-17

CCSD : 6815

Title : Molecular cloning and function analysis of sialyltranferase

Authors : Tsuji S

Info : J Biochem (1996) 120: 1-13

Other Data : 2010-12-17

CCSD : 6909

Title : Molecular cloning and function analysis of sialyltranferase

Authors : Tsuji S

Info : J Biochem (1996) 120: 1-13

Other Data : 2010-12-17

CCSD : 9909

Title : Comparison of the carbon-13 NMR spectra of gangliosides GM1 with those of GM1-oligosaccharide and asialo-GM1

Authors : Sillerud LO; Yu RK

Info : Carbohydr Res (1983) 113: 173-188

Other Data : 2010-12-17

CCSD : 11660

Title : Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine

Authors : Breimer ME; Hansson GC; Karlsson KA; Leffler H

Info : J Biol Chem (1982) 257: 557-568

TAXID : 10116 Other Data : intestine Other Data : 2010-12-17

CCSD : 14072

Title : Analysis of cellular expression of gangliosides by gene transfection. fps, ras & src) invariably express sialosylparagloboside

Authors : Nakaishi H; Sanai Y; Shibuya M; Nagai Y

Info : Biochem Biophys Res Commun (1988) 150: 766-774

TAXID : 10116 Other Data : 2010-12-17

CCSD : 14550

Title : Gangliosides of murine B-lymphoma MOPC-406

Authors : Dyatlovitskaya EV; Somova OG; Kogtev LS; Bergelson LD

Info : Biochemistry (Mosc) (1986) 51: 1308-1314

TAXID : 10090 Other Data : B-lymphoma Other Data : 2010-12-17

CCSD : 14849

Title : Qualitative differences in position of sialylation and surface expression of glycolipids between murine lymphomas with low metastatic disialoganglioside (GD1.alpha.) from Eb cells

Authors : Murayama K; Levery SB; Schirrmacher V; Hakomori SI

Info : Cancer Res (1986) 46: 1395-1402

TAXID : 10090 Other Data : 2010-12-17

CCSD : 14871

Title : Glycosphingolipids of lectin-resistant mutants of the highly metastatic mouse tumor cell line, MDAY-D2

Authors : Laferte S; Fukuda MN; Fukuda M; Dell A; Dennis JW

Info : Cancer Res (1987) 47: 150-159

TAXID : 10090 Other Data : lymphoreticular tumor Other Data : 2010-12-17

CCSD : 15600

Title : Structural characterization of gangliosides from murine T lymphocytes

Authors : Muething J; Egge H; Kniep B; Muehlradt PF

Info : Eur J Biochem (1987) 163: 407-416

TAXID : 10090 Other Data : lymphocyte Other Data : 2010-12-17

CCSD : 18649

Title : Gangliosides of murine T lymphocyte subpopulations

Authors : Muething J; Schwinzer B; Peter-Katalinic J; Egge H; Muehlradt PF

Info : Biochemistry (1989) 28: 2923-2929

TAXID : 10090 Other Data : T lymphocyte subpopulation Other Data : 2010-12-17

CCSD : 18921

Title : Biosynthesis of GM1b and similar neolactoseries gangliosides by a partially purified chicken skeletal muscle sialyltransferase. Effect of sphingomyelin and acetylcholine

Authors : Dasgupta S; Chien JL; Hogan EL

Info : Biochim Biophys Acta (1990) 1036: 11-17

Other Data : 2010-12-17

CCSD : 19901

Title : Synthetic studies on sialoglycoconjugates. Part 26. Regio- and stereoselective synthesis of ganglioside GM1b and some positional analogs

Authors : Prabhanjan H; Kameyama A; Ishida H; Kiso M; Hasegawa A

Info : Carbohydr Res (1991) 220: 127-143

Other Data : 2010-12-17

CCSD : 20346

Title : Expression of plasma membrane and cell surface phospholipids and gangliosides of chick embryo neurons grown in primary cultures: developmental studies

Authors : Lelong I; Frechard E; Cremel G; Langley K; Rebel G; Vincendon G; Mersel M

Info : Dev Neurosci (1991) 13: 54-60

TAXID : 9031 Other Data : neuron culture Other Data : 2010-12-17

CCSD : 20354

Title : Variation of influenza viruses and their recognition of the receptor sialo-sugar chains

Authors : Suzuki Y

Info : Yakugaku Zasshi (1993) 113: 556-578

Other Data : 2010-12-17

CCSD : 20914

Title : Detection of gangliosides by direct binding of Limax flavus agglutinin to thin layer chromatograms

Authors : Kielczynski W; Harrison LC

Info : Glycoconj J (1990) 7: 75-84

Other Data : 2010-12-17

CCSD : 22087

Title : The presence of sialidase-sensitive sialosylgangliotetraosyl ceramide Escherichia coli-activated macrophages from the C3H/HeJ mouse

Authors : Yohe HC; Cuny CL; Macala LJ; Saito M; McMurray WJ; Ryan JL

Info : J Immunol (1991) 146: 1900-1908

Other Data : 2010-12-17

CCSD : 22215

Title : Gangliosides in human fetal brain

Authors : Svennerholm L; Rynmark BM; Vilbergsson G; Fredman P; Gottfries J; Maansson JE; Percy A

Info : J Neurochem (1991) 56: 1763-1768

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 23093

Title : Synthetic studies on cell-surface glycans. 71. A stereocontrolled total synthesis of a ganglio-ganglioside GM1b, IV3NeuAc.alpha.GgOse4Cer

Authors : Sugimoto M; Fujikura K; Nunomura S; Horisaki T; Ito Y; Ogawa T

Info : Tetrahedron Lett (1990) 31: 385-388

Other Data : 2010-12-17

CCSD : 24777

Title : Appearance of a novel type of ganglioside (GD1.alpha.) in a differentiation resistance clone of mouse myeloid leukemia cells, M1-R1

Authors : Taki T; Maeda H; Arai K; Matsumoto M; Kon K; Ando S

Info : Cell Struct Funct (1988) 13: 61-72

TAXID : 10090 Other Data : myeloid leukemia Other Data : 2010-12-17

CCSD : 25257

Title : Ganglioside alterations in YAC-1 cells cultivated in serum- supplemented and serum-free growth medium

Authors : Muething J; Poertner A; Jaeger V

Info : Glycoconj J (1992) 9: 265-273

TAXID : 10090 Other Data : 2010-12-17

CCSD : 25402

Title : Genetic polymorphism of ganglioside expression in mouse organs

Authors : Nakamura K; Hashimoto Y; Yamakawa T; Suzuki A

Info : J Biochem (1988) 103: 201-208

TAXID : 10090 Other Data : 2010-12-17

CCSD : 29004

Title : Molecular cloning and expression of Gal.beta.1,3GalNAc.alpha.2,3- sialyltransferase from mouse brain

Authors : Lee YC; Kurosawa N; Hamamoto T; Nakaoka T; Tsuji S

Info : Eur J Biochem (1993) 216: 377-385

Other Data : 2010-12-17

CCSD : 31659

Title : Cloning of a novel .alpha.2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups

Authors : Kitagawa H; Paulson JC

Info : J Biol Chem (1994) 269: 1394-1401

Other Data : 2010-12-17

CCSD : 32067

Title : The ganglioside GD1.alpha., IV3Neu5Ac,III6Neu5Ac-GgOse4Cer, is a major disialoganglioside in the highly metastatic murine lymphoreticular tumour cell line MDAY-D2

Authors : Muething J; Peter-Katalinic J; Hanisch FG; Unland F; Lehmann J

Info : Glycoconj J (1994) 11: 153-162

TAXID : 10090 Other Data : lymphoreticular tumor Other Data : 2010-12-17

CCSD : 32694

Title : Generation of one set of monoclonal antibodies specific for a-pathway ganglio-series gangliosides

Authors : Kotani M; Ozawa H; Kawashima I; Ando S; Tai T

Info : Biochim Biophys Acta (1992) 1117: 97-103

Other Data : 2010-12-17

CCSD : 32753

Title : Biosynthesis and shedding of murine lymphoma gangliosides

Authors : Li R; Gage D; Ladisch S

Info : Biochim Biophys Acta (1993) 1170: 283-290

Other Data : 2010-12-17

CCSD : 33572

Title : NMR and computational studies of interactions between remote residues in gangliosides

Authors : Scarsdale JN; Prestegard JH; Yu RK

Info : Biochemistry (1990) 29: 9843-9855

Other Data : 2010-12-17

CCSD : 33628

Title : In vitro synthesis of disialoganglioside (GD1.alpha.) from asialo-GM1 using sialyltransferases in rat liver vesicles

Authors : Hidari KI-PJ; Kawashima I; Tai T; Inagaki F; Nagai Y; Sanai Y

Info : Eur J Biochem (1994) 221: 603-609

Other Data : 2010-12-17

CCSD : 33676

Title : Substrate specificity of .alpha.2-3-sialyltransferases in ganglioside biosynthesis of rat liver golgi

Authors : Iber H; van Echten G; Sandhoff K

Info : Eur J Biochem (1991) 195: 115-120

Other Data : 2010-12-17

CCSD : 33956

Title : Cloning and expression of Gal.beta.1,3GalNAc-specific GalNAc .alpha.2, 6sialyltransferase

Authors : Kurosawa N; Kojima N; Inoue M; Hamamoto T; Tsuji S

Info : J Biol Chem (1994) 269: 19048-19053

Other Data : 2010-12-17

CCSD : 34100

Title : Generation of monoclonal antibodies specific for ganglioside lactone: Evidence of the expression of lactone on human melanoma cells

Authors : Kawashima I; Kotani M; Ozawa H; Suzuki M; Tai T

Info : Int J Cancer (1994) 58: 263-268

Other Data : 2010-12-17

CCSD : 34860

Title : Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors

Authors : Sung CC; Pearl DK; Coons SW; Scheithauer BW; Johnson PC; Yates AJ

Info : Cancer (1994) 74: 3010-3022

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 36491

Title : Structural characterization of gangliosides from resting and endotoxin-stimulated murine B lymphocytes

Authors : Poertner A; Peter-Katalinic J; Brade H; Unland F; Buentemeyer H; Muething J

Info : Biochemistry (1993) 32: 12685-12693

TAXID : 10090 Other Data : B-cells Other Data : 2010-12-17

CCSD : 36572

Title : Glycosphingolipids of rat T cells. Predominance of asialo-GM1 and GD1c

Authors : Nohara K; Nakauchi H; Spiegel S

Info : Biochemistry (1994) 33: 4661-4666

TAXID : 10116 Other Data : T-cells, B-cells Other Data : 2010-12-17

CCSD : 36595

Title : Kinetic properties and acceptor substrate preferences of two kinds of Gal.beta.1,3GalNAc .alpha.2,3-sialyltransferase from mouse brain

Authors : Kojima N; Lee YC; Hamamoto T; Kurosawa N; Tsuji S

Info : Biochemistry (1994) 33: 5772-5776

Other Data : 2010-12-17

CCSD : 37078

Title : Ganglioside distribution in murine neural tumors

Authors : Seyfried TN; El-Abbadi M; Roy ML

Info : Mol Chem Neuropathol (1992) 17: 147-167

TAXID : 10090 Other Data : brain Other Data : 2010-12-17

CCSD : 37100

Title : Influence of growth environment on the ganglioside composition of an experimental mouse brain tumor

Authors : El-Abbadi M; Seyfried TN

Info : Mol Chem Neuropathol (1994) 21: 273-285

Other Data : 2010-12-17

CCSD : 37220

Title : Designation and schematic structure of gangliosides and allied glycosphingolipids

Authors : Svennerholm L

Info : Prog Brain Res (1994) 101: 11-14

Other Data : 2010-12-17

CCSD : 39528

Title : Characteristic expression of GD1.alpha.-ganglioside during lactation in murine mammary gland

Authors : Momoeda M; Momoeda K; Takamizawa K; Matsuzawa A; Hanaoka K; Taketani Y; Iwamori M

Info : Biochim Biophys Acta (1995) 1256: 151-156

TAXID : 10090 Other Data : mammary gland Other Data : 2010-12-17

CCSD : 40447

Title : In situ accessibility of murine macrophage gangliosides

Authors : Macala LJ; Yohe HC

Info : Glycobiology (1995) 5: 67-75

TAXID : 10090 Other Data : macrophage Other Data : 2010-12-17

CCSD : 40684

Title : Sialidase of swine influenza A viruses: variation of the recognition specificities for sialyl linkages and for the molecular species of sialic acid with the year of isolation

Authors : Xu G; Suzuki T; Maejima Y; Mizoguchi T; Tsuchiya M; Kiso M; Hasegawa A; Suzuki Y

Info : Glycoconj J (1995) 12: 156-161

Other Data : 2010-12-17

CCSD : 44040

Title : Ganglioside metabolism- topology and regulation

Authors : Sandhoff K; van Echten G

Info : Adv Lipid Res (1993) 26: 119-142

Other Data : 2010-12-17

CCSD : 44067

Title : Molecular approaches to studying the intracellular trafficking of glycosphingolipids

Authors : Young WW

Info : Adv Lipid Res (1993) 26: 161-179

Other Data : 2010-12-17

CCSD : 44836

Title : The chemical constitution of gangliosides of the vertebrate nervous system

Authors : Wiegandt H

Info : Behav Brain Res (1995) 66: 85-97

TAXID : 9913 Other Data : brain Other Data : 2010-12-17

CCSD : 44960

Title : .beta.1-4N-acetylgalactosaminyltransferase can synthesize both asialo- glycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a .beta.1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F

Authors : Hidari KI-PJ; Ichikawa S; Furukawa K; Yamasaki M; Hirabayashi Y

Info : Biochem J (1994) 303: 957-965

TAXID : 10029 Other Data : CHO cells Other Data : 2010-12-17

CCSD : 45473

Title : An improved method for preparation of perbenzoylated ganglioside- derived sialic acids and nanogram detection of N-acetyl- and N-glycolyl neuraminic acid by high performance liquid chromatography

Authors : Unland F; Muthing J

Info : Biomed Chromatogr (1992) 6: 155-159

Other Data : 2010-12-17

CCSD : 46844

Title : A unique biosynthetic pathway for gangliosides exists in Xenopus laevis oocytes

Authors : Hidari KI-PJ; Nagai Y; Sanai Y

Info : FEBS Lett (1994) 353: 25-28

TAXID : 8355 Other Data : oocyte Other Data : 2010-12-17

CCSD : 47171

Title : Structural studies of gangliosides from the YAC-1 mouse lymphoma cell line by immunological detection and fast atom bombardment mass spectrometry

Authors : Muething J; Peter-Katalinic J; Hanisch FG; Neumann U

Info : Glycoconj J (1991) 8: 414-423

TAXID : 10090 Other Data : lymphocyte, T cells Other Data : 2010-12-17

CCSD : 48579

Title : Ganglioside biosynthesis in mouse embryos: sialyltransferase IV and the asialo pathway

Authors : Seyfried TN; Novikov AM; Irvine RA; Brigande JV

Info : J Lipid Res (1994) 35: 993-1001

Other Data : 2010-12-17

CCSD : 49461

Title : Gangliosides of anencephalic and fetal brain-immunostaining on thin- layer chromatograms

Authors : Cacic M

Info : Neuroreport (1995) 6: 389-393

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 50223

Title : Development regulation of ganglioside metabolism

Authors : Yu RK

Info : Prog Brain Res (1994) 101: 31-44

Other Data : 2010-12-17

JCGGDB ID JCGG-STR027271

Glycan Information

External Links