JCGG-STR026373:JCGGDB ID

JCGGDB Glycan Structure Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)

Glycan Information

Glyco Tree get Image

Composition

Hex 2 Neu5Ac 3
Mass Value Search

Gal 1 Glc 1 Neu5Ac 3
Structural Isomer Search

Descriptors Computed from Structure

InChIKey	BNBYYQKSOHNRMH-SRIZXVEOSA-N
InChI	InChI=1S/C45H73N3O35/c1-12(54)46-23-15(57)4-43(40(69)70,80-34(23)26(61)18(60)7-49)78-20(9-51)28(63)35-24(47-13(2)55)16(58)5-44(81-35,41(71)72)79-21(10-52)29(64)36-25(48-14(3)56)17(59)6-45(82-36,42(73)74)83-37-27(62)19(8-50)76-39(32(37)67)77-33-22(11-53)75-38(68)31(66)30(33)65/h15-39,49-53,57-68H,4-11H2,1-3H3,(H,46,54)(H,47,55)(H,48,56)(H,69,70)(H,71,72)(H,73,74)/t15-,16-,17-,18+,19+,20+,21+,22+,23+,24+,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35+,36+,37-,38+,39-,43+,44+,45-/m0/s
SMILES	CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@H](CO)[C@@H](O)[C@@H]2O[C@@](C[C@H](O)[C@H]2NC(C)=O)(O[C@H](CO)[C@@H](O)[C@@H]2O[C@@](C[C@H](O)[C@H]2NC(C)=O)(O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)C(O)=O)C(O)=O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

Mass

	Monoisotopic Mass	Average Mass
Underivatised Oligosaccharides	1215.4023 (A_n=2 ) = 633.2115+ A[291.0954]_n=2	1216.0737 (A_n=2 ) = 633.5579+ A[291.2579]_n=2
Permethylated Oligosaccharides	1537.7625 (A_n=2 ) = 815.4151+ A[361.1737]_n=2	1538.6919 (A_n=2 ) = 815.9073+ A[361.3923]_n=2
Peracetylated Oligosaccharides	1929.582 (A_n=2 ) = 1095.3278+ A[417.1271]_n=2	1930.7076 (A_n=2 ) = 1095.968+ A[417.3698]_n=2

Glycan Motifs

Motif ID	Structure / SubStructure Name	Note
JCGG-MOTIF4082	Poly-N-Acetylneuraminic Acid	NON-Reducing Terminal

ID History Deleted Version

JCGG-STR031598(2) JCGG-STR033508(3)

External Links

GlycoEpitope (Antiglycan Antibody)

GlycoEpitope GLPD-000028 GLPD-000028

Name:   GT3
Description:   II³Neu5Ac₃LacCer
Reducing terminal:   (b-1)Cer

GMDB (MSⁿ)

GMDB OSO-00025e

JCGG	JCGG JGD-001243 JGD-001243 JCGG JGD-000574 JGD-000574 Reducing terminal: (b-1)Cer

LipidBank (Spectral Data)

LipidBank GSG1107 GSG1107

Description: NeuAca2-8NeuAca2-8NeuAca2-3Galb1-4GlcCer
Reducing terminal: (b-)Cer

LipidBank GSG3049 GSG3049

Description: N-acetylneraminyla2-8N-acetylneraminyla2-8N-acetylneraminyla2-3galactosylb1-4glucosylceramide
Reducing terminal: (b-)Cer

GlycomeDB (Structure)

GlycomeDB 538 538

KEGG (Structure)

KEGG G00118 G00118

PACDB(Pathogen adhesion)

Pathogen:	Influenza virus (A/PR/8/34; H1N1; human)
Glycan Name:	GT3 [ Not Binding]

Pathogen:	Influenza virus (B/Lee/40; human)
Glycan Name:	GT3 [ Not Binding]

Pathogen:	Influenza virus (C/Ann Arbor/1/50; human)
Glycan Name:	GT3 [ Not Binding]

CarbBank

CCSD : 775

Title : Structures of some new complex gangliosides of fish brain

Authors : Yu RK; Ando S

Info : Adv Exp Med Biol (1980) 125: 33-45

Other Data : brain Other Data : 2010-12-17

CCSD : 6835

Title : Molecular cloning and function analysis of sialyltranferase

Authors : Tsuji S

Info : J Biochem (1996) 120: 1-13

Other Data : 2010-12-17

CCSD : 9329

Title : Differential expression of gangliosides and galactolipids in fetal human oligodendrocytes and astrocytes in culture

Authors : Satoh J; Tai T; Kim SU

Info : Dev Brain Res (1996) 93: 172-181

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : GalC+ oligodendrocytes, GFAP+ astrocytes Other Data : 2010-12-17

CCSD : 13522

Title :

Authors : Yu RK; Ando S

Info : Trans Am Soc Neurochem (1978) 9: 135

Other Data : 2010-12-17

CCSD : 15544

Title : Glycolipid core structure switching from globo- to lacto- and ganglio- series during rentinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells

Authors : Fenderson BA; Andrews PW; Nudelman E; Clausen H; Hakomori SI

Info : Dev Biol (1987) 122: 21-34

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 16235

Title : Gangliosides of bovine buttermilk: isolation and characterization of a novel monosialoganglioside with a new branching structure

Authors : Takamizawa K; Iwamori M; Mutai M; Nagai Y

Info : J Biol Chem (1986) 261: 5625-5630

TAXID : 9913 Other Data : milk, buttermilk Other Data : 2010-12-17

CCSD : 18629

Title : Glycolipid glycosyltransferases in human embryonal carcinoma cells during retinoic acid induced differentiation

Authors : Chen C; Fenderson BA; Andrews PW; Hakomori S

Info : Biochemistry (1989) 28: 2229-2238

Other Data : 2010-12-17

CCSD : 21343

Title : A new monoclonal antibody directed to sialyl.alpha.2- 3lactoneotetraosylceramide and its application for detection of human gastrointestinal neoplasms

Authors : Suzuki Y; Nishi H; Hidari K; Hirabayashi Y; Matsumoto M; Kobayashi T; Watarai S; Yasuda T; Nakayama J; Maeda H; Katsuyama T; Kanai M; Kiso M; Hasegawa A

Info : J Biochem (1991) 109: 354-360

Other Data : 2010-12-17

CCSD : 23921

Title : The glycosphingolipid composition of the human hepatoma cell line, Hep-G2

Authors : Spitalnik PF; Danley JM; Burger SR; Spitalnik SL

Info : Arch Biochem Biophys (1989) 273: 578-591

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : liver Other Data : 2010-12-17

CCSD : 25576

Title : Monoclonal antibody A2B5, which detects cell surface antigens, binds to ganglioside GT3 (II3(NeuAc)3LacCer) and to its 9-O-acetylated derivative

Authors : Dubois C; Manuguerra JC; Hauttecoeur B; Maze J

Info : J Biol Chem (1990) 265: 2797-2803

Other Data : 2010-12-17

CCSD : 25661

Title : O-Acetylated gangliosides in bovine buttermilk. Characterization of 7- O-acetyl, 9-O-acetyl, and 7,9-di-O-acetyl GD3

Authors : Ren S; Scarsdale JN; Ariga T; Zhang Y; Klein RA; Hartmann R; Kushi Y; Egge H; Yu RK

Info : J Biol Chem (1992) 267: 12632-12638

Other Data : buttermilk Other Data : 2010-12-17

CCSD : 26607

Title : Interferon-gamma alters expression of endothelial cell-surface glycosphingolipids

Authors : Gillard BK; Jones MA; Turner AA; Lewis DE; Marcus DM

Info : Arch Biochem Biophys (1990) 279: 122-129

Other Data : 2010-12-17

CCSD : 27262

Title : Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine

Authors : Andrews PW; Nudelman E; Hakomori S; Fenderson BA

Info : Differentiation (1990) 43: 131-138

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 27470

Title : Variable subcellular localization of glycosphingolipids

Authors : Gillard BK; Thurmon LT; Marcus DM

Info : Glycobiology (1993) 3: 57-67

Other Data : 2010-12-17

CCSD : 29476

Title : The c-series gangliosides GT3, GT2 and GP1c are formed in rat liver Golgi by the same set of glycosyltransferases that catalyse the biosynthesis of asialo-, a- and b-series gangliosides

Authors : Iber H; Zacharias C; Sandhoff K

Info : Glycobiology (1992) 2: 137-142

Other Data : 2010-12-17

CCSD : 31902

Title : A new O-acetylated trisialoganglioside, 9-O-acatyl GT2, in cod brain

Authors : Waki H; Masuzawa A; Kon K; Ando S

Info : J Biochem (1993) 114: 459-462

TAXID : 48550 Other Data : brain Other Data : 2010-12-17

CCSD : 32692

Title : Generation of one set of monoclonal antibodies specific for a-pathway ganglio-series gangliosides

Authors : Kotani M; Ozawa H; Kawashima I; Ando S; Tai T

Info : Biochim Biophys Acta (1992) 1117: 97-103

Other Data : 2010-12-17

CCSD : 32844

Title : Gangliosides in bovine milk. Changes in content and distribution of individual ganglioside levels during lactation

Authors : Puente R; Garcia-Pardo LA; Hueso P

Info : Biol Chem Hoppe-Seyler (1992) 373: 283-288

TAXID : 9913 Other Data : milk Other Data : 2010-12-17

CCSD : 33688

Title : Substrate specificity of .alpha.2-3-sialyltransferases in ganglioside biosynthesis of rat liver golgi

Authors : Iber H; van Echten G; Sandhoff K

Info : Eur J Biochem (1991) 195: 115-120

Other Data : 2010-12-17

CCSD : 35383

Title : Regulation of ganglioside composition and synthesis is different in developing chick retinal pigment epithelium and neural retina

Authors : Daniotti JL; Landa CA; Maccioni HJF

Info : J Neurochem (1994) 62: 1131-1136

TAXID : 9031 Other Data : retina Other Data : 2010-12-17

CCSD : 35395

Title : Activities of five different sialyltransferases in fish and rat brains

Authors : Freischutz B; Saito M; Rahmann H; Yu RK

Info : J Neurochem (1994) 62: 1965-1973

TAXID : 8127 Other Data : brain Other Data : 2010-12-17

CCSD : 35490

Title : In vitro modulation of changes in ganglioside patterns of differentiating neurons in the presence of an anti-GM1 antibody

Authors : Allende ML; Panzetta P

Info : J Neurosci Res (1994) 37: 497-505

TAXID : 9031 Other Data : retina cells Other Data : 2010-12-17

CCSD : 36146

Title : Gangliosides and modulation of the function of neural cells

Authors : Tettamanti G; Riboni L

Info : Adv Lipid Res (1993) 25: 235-267

Other Data : 2010-12-17

CCSD : 37227

Title : Designation and schematic structure of gangliosides and allied glycosphingolipids

Authors : Svennerholm L

Info : Prog Brain Res (1994) 101: 11-14

Other Data : 2010-12-17

CCSD : 38139

Title : Glycolipids of germ cell tumors: extended globo-series glycolipids are a hallmark of human embryonal carcinoma cells

Authors : Wenk J; Andrews PW; Casper J; Hata JI; Pera MF; Von Keitz A; Damjanov I; Fenderson BA

Info : Int J Cancer (1994) 58: 108-115

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : germ cells Other Data : 2010-12-17

CCSD : 44052

Title : Ganglioside metabolism- topology and regulation

Authors : Sandhoff K; van Echten G

Info : Adv Lipid Res (1993) 26: 119-142

Other Data : 2010-12-17

CCSD : 44824

Title : The chemical constitution of gangliosides of the vertebrate nervous system

Authors : Wiegandt H

Info : Behav Brain Res (1995) 66: 85-97

Other Data : brain Other Data : 2010-12-17

CCSD : 45154

Title : Blood serum gangliosides and antibodies to gangliosides

Authors : Dyatlovitskaya EV

Info : Biochemistry (Mosc) (1992) 57: 689-693

Other Data : 2010-12-17

CCSD : 50224

Title : Development regulation of ganglioside metabolism

Authors : Yu RK

Info : Prog Brain Res (1994) 101: 31-44

Other Data : 2010-12-17

JCGGDB ID JCGG-STR026373

Glycan Information

External Links