JCGG-STR012452:JCGGDB ID

Glycan Information

Glyco Tree get Image

Composition

Descriptors Computed from Structure

Mass

Glycan Motifs

Motif ID	Structure / SubStructure Name	Note
JCGG-MOTIF3009	neolacto	Reducing Terminal
JCGG-MOTIF4062	Paragloboside	Reducing Terminal
JCGG-MOTIF4032	SSEA-1	NON-Reducing Terminal

External Links

GlycoEpitope (Antiglycan Antibody)

Name:   Le^x heptasaccharide
Alias Name:   y₂
Description:   V³FucnLc₆Cer
Reducing terminal:   (b-1)Cer

JCGG	JCGG JGD-000648 JGD-000648 Reducing terminal: (b-1)Cer

LipidBank (Spectral Data)

GSG1269

Description: Galb1-4(Fuca1-3)GlcNAcb1-3Galb1-4GlcNAcb1-3Galb1-4Glcb1-1Cer
Reducing terminal: (b-)Cer

GlycomeDB (Structure)

2155

KEGG (Structure)

G00089

PACDB(Pathogen adhesion)

Pathogen:	Escherichia coli (Enterotoxigenic(ETEC); K88)
Glycan Name:	Fuc-nLc6 (V3) [ Not Binding]

CarbBank

CCSD : 1304

Title : A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen, SSEA-1

Authors : Kannagi R; Nudelman E; Levery SB; Hakomori S

Info : J Biol Chem (1982) 257: 14865-14874

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : erythrocyte Other Data : 2010-12-17

CCSD : 1305

Title : Structures of glycosphingolipids isolated from human granulocytes. The presence of a series of linear poly-N-acetyllactosaminylceramide and its significance in glycolipids of whole blood cells

Authors : Fukuda MN; Dell A; Oates JE; Wu P; Klock JC; Fukuda M

Info : J Biol Chem (1985) 260: 1067-1082

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : granulocyte Other Data : 2010-12-17

CCSD : 5390

Title : Specificity of fucose transfer to GlcNAc residues of extended chain neolacto-series glycolipids catalyzed by human .alpha.1-3fucosyltransferases: effect on the lipidic environment on the myeloid enzyme form

Authors : Holmes EH; Macher BA

Info : Arch Biochem Biophys (1993) 301: 190-199

Other Data : 2010-12-17

CCSD : 16153

Title : Enzymic basis for the accumulation of glycolipids with X and dimeric X determinants in human lung cancer cells (NCI-H69)

Authors : Holmes EH; Ostrander GK; Hakomori S

Info : J Biol Chem (1985) 260: 7619-7627

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : lung Other Data : 2010-12-17

CCSD : 16416

Title : Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation

Authors : Holmes EH; Ostrander GK; Clausen H; Graem N

Info : J Biol Chem (1987) 262: 11331-11338

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : colon Other Data : 2010-12-17

CCSD : 16453

Title : Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed .beta.1-3N-acetylglucosaminyltransferase

Authors : Holmes EH; Hakomori S; Ostrander GK

Info : J Biol Chem (1987) 262: 15649-15658

Other Data : 2010-12-17

CCSD : 17365

Title : Isolation and purification of glycosphingolipids by high-performance liquid chromatography

Authors : Kannagi R; Watanabe K; Hakomori S

Info : Methods Enzymol (1987) 138: 3-12

Other Data : 2010-12-17

CCSD : 20737

Title : Bioorganic synthesis of dimeric Lex (difucosyl Y2 antigen; III3FucV3- FucnLc6Cer) and analogs thereof

Authors : Nudelman E; Sadozai K; Clausen H; Hakomori S; Stroud MR

Info : Eur Pat Appl (1990) : 1-26

Other Data : 2010-12-17

CCSD : 21487

Title : Specific interaction between Lex and Lex determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells

Authors : Eggens I; Fenderson B; Toyokuni T; Dean B; Stroud M; Hakomori S

Info : J Biol Chem (1989) 264: 9476-9484

Other Data : 2010-12-17

CCSD : 21921

Title : Alteration of lacto-series glycolipid glycosyltransferase activities in human colonic adenocarcinoma DLD-1 cells after culture in N,N- dimethylformamide-containing medium

Authors : Holmes EH; Greene TG

Info : J Cell Biochem (1990) 44: 93-105

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : colon Other Data : 2010-12-17

CCSD : 22620

Title : Distribution of VIM-2 and SSEA-1 glycoconjugate epitopes among human leukocytes and leukemia cells

Authors : Macher BA; Beckstead JH

Info : Leuk Res (1990) 14: 119-130

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : leukocyte Other Data : 2010-12-17

CCSD : 23136

Title : Hybridomas producing monoclonal antibodies to mono-, di-, and trifucosylated type 2 chain of glycolipids

Authors : Hakomori S

Info : US Pat Appl (1989) : 1-24

Other Data : 2010-12-17

CCSD : 23932

Title : Antibody 624H12, which detects lung cancer at early stages, recognizes a sugar sequence in the glycosphingolipid difucosylneolactonorhexaosylceramide (V3FucIII3FucnLc6Cer)

Authors : Kyogashima M; Mulshine J; Linnoila RI; Jensen S; Magnani JL; Nudelman E; Hakomori S; Ginsburg V

Info : Arch Biochem Biophys (1989) 275: 309-314

Other Data : 2010-12-17

CCSD : 25470

Title : Biosynthesis of the sialyl-Lex determinant carried by type 2 chain glycosphingolipids (IV3NeuAcIII3FucnLc4, VI3NeuAcV3FucnLc6, and VI3NeuAcIII3V3Fuc2nLc6) in human lung carcinoma PC9 cells

Authors : Holmes EH; Ostrander GK; Hakomori S

Info : J Biol Chem (1986) 261: 3737-3743

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : lung Other Data : 2010-12-17

CCSD : 25823

Title : Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood-group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that recognize crossreacting antigens on LOS and human erythrocytes

Authors : Mandrell RE; Griffiss JML; Macher BA

Info : J Exp Med (1988) 168: 107-126

Other Data : 2010-12-17

CCSD : 25848

Title : Glycolipid antigens of human polymorphonuclear neutrophils and the inducible HL-60 myeloid leukemia line

Authors : Symington FW; Hedges DL; Hakomori S

Info : J Immunol (1985) 134: 2498-2506

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 28513

Title : Rostrocaudal expression of antibody NHK-1-reactive glycolipids in mouse cerebellum: relationship to developmental compartments and leaner mutation

Authors : Nair SM; Prasadarao N; Tobet SA; Jungalwala FB

Info : J Comp Neurol (1993) 332: 282-292

Other Data : 2010-12-17

CCSD : 29780

Title : Possible role of ceramide in defining structure and function of membrane glycolipids

Authors : Kannagi R; Nudelman E; Hakomori SI

Info : Proc Natl Acad Sci U S A (1982) 79: 3470-3474

Other Data : 2010-12-17

CCSD : 33618

Title : Blood group antigens on human erythrocytes-distribution, structure and possible functions

Authors : King MJ

Info : Biochim Biophys Acta (1994) 1197: 15-44

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : erythrocyte Other Data : 2010-12-17

CCSD : 35917

Title : Further studies on cell adhesion based on Lex-Lex interaction, with new approaches: embryoglycan aggregation of F9 teratocarcinoma cells, and adhesion of various tumour cells based on Lex expression

Authors : Kojima N; Fenderson BA; Stroud MR; Goldberg RI; Habermann R; Toyokuni T; Hakomori SI

Info : Glycoconj J (1994) 11: 238-248

Other Data : 2010-12-17

CCSD : 44584

Title : Fucosylated glycosphingolipids of human myeloid cells

Authors : Kong RKM; Barrios A; Knapp W; Macher BA

Info : Arch Biochem Biophys (1993) 300: 677-683

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : myeloid leukocyte Other Data : 2010-12-17

JCGGDB ID JCGG-STR012452

Glycan Information

External Links