JCEG ID | JCEG216 | |||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Name | gly-6 WormBase NCBI Gene | |||||||||||||||||||||||||||||||||||||||||||||||||||
Human Ortholog |
GGDB:GALNT1 OMIM:
|
|||||||||||||||||||||||||||||||||||||||||||||||||||
Family Name | ppGalNAcT | |||||||||||||||||||||||||||||||||||||||||||||||||||
Locus Tag | H38K22.5 | |||||||||||||||||||||||||||||||||||||||||||||||||||
RNAi phenotype |
|
|||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence Features | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence | CDS |
|||||||||||||||||||||||||||||||||||||||||||||||||||
Protein |
||||||||||||||||||||||||||||||||||||||||||||||||||||
References |
Hagen FK, Nehrke K J. Biol. Chem. (1998) 273 (14) :8268-77 [PMID : 9525933] cDNA cloning and expression of a family of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase sequence homologs from Caenorhabditis elegans. Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schafer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H J. Biol. Chem. (2002) 277 (25) :22623-38 [PMID : 11925450] Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila. Wang H, Spang A, Sullivan MA, Hryhorenko J, Hagen FK Mol. Biol. Cell (2005) 16 (9) :4202-13 [PMID : 15987734] The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation. Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation. Lee W, Kim KR, Singaravelu G, Park BJ, Kim DH, Ahnn J, Yoo YJ Proteomics (2006) 6 (4) :1329-39 [PMID : 16404716] Alternative chaperone machinery may compensate for calreticulin/calnexin deficiency in Caenorhabditis elegans. LeGendre JB, Campbell ZT, Kroll-Conner P, Anderson P, Kimble J, Wickens M J. Biol. Chem. (2012) 288 (4) :2532-45 [PMID : 23195953] RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. Bennett EP, Mandel U, Clausen H, Gerken TA, Fritz TA, Tabak LA Glycobiology (2012) 22 (6) :736-56 [PMID : 22183981] Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family. |
Functional Descriptions |
gly-6 |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Deletion Mutants | gk350 ok1912 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
In Situ | In Situ | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Expression |
Expression
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
WBGene00001631 Phenotype Homology_paralog |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Phenotype | Definition | RNAi / Allele |