| STREAM | RAF | p-value | OR | BETA | CI | Study |
| UPSTREAM |
|
0.000002
(Conditioned on rs2303759)
|
1.08
|
|
[1.07-1.09] |
21833088
|
|
Sawcer S 2011-08-11 Nature
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
| MAPPED |
|
0.00000004
|
1.183432
|
|
[1.15-1.22] |
25574825
|
|
Baurecht H 2015-01-08 Am J Hum Genet
Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms.
|
| MAPPED |
|
0.000000000000000000000000000000000004
|
|
70.21
(pg/ml increase)
|
[59.37-81.05] |
22367966
|
|
Lin X 2012-02-24 Hum Mol Genet
Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.
|
| MAPPED |
|
0.00000000000000000000000000000000000000000000000000000001
|
|
|
|
24941225
|
|
Liang Y 2014-06-18 PLoS One
Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
|
| MAPPED |
0.53 |
0.0000000000001
(DSGEGDFXAEGGGVR/ADpSGEGDFXAEGGGVR)
|
|
0.045
(unit increase)
|
[0.033-0.057] |
24816252
|
|
Shin SY 2014-05-11 Nat Genet
An atlas of genetic influences on human blood metabolites.
|
| MAPPED |
0.53 |
0.00000000000000000003
(vitamin B12)
|
|
49.77
(pg/ml increase)
|
[37.09-62.45] |
19303062
|
|
Tanaka T 2009-03-18 Am J Hum Genet
Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.
|
| UPSTREAM |
0.52 |
0.00000005
(Single Height-males)
|
|
0.07
(unit increase)
|
[0.043-0.097] |
23449627
|
|
Cousminer DL 2013-02-27 Hum Mol Genet
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
|
| MAPPED |
0.49 |
0.0000000002
|
|
1.27
(mg/dL increase)
|
[0.86-1.68] |
20686565
|
|
Teslovich TM 2010-08-05 Nature
Biological, clinical and population relevance of 95 loci for blood lipids.
|
| MAPPED |
0.49 |
0.00000000000000005
|
|
0.09
(pg/ml decrease)
|
[0.07-0.11] |
18776911
|
|
Hazra A 2008-09-07 Nat Genet
Common variants of FUT2 are associated with plasma vitamin B12 levels.
|
| UPSTREAM |
0.487 |
0.000000000007
|
1.07
|
|
[1.04-1.11] |
21102463
|
|
Franke A 2010-11-21 Nat Genet
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
| MAPPED |
0.483 |
0.000000000000001
|
1.107
|
|
[1.071-1.143] |
23128233
|
|
Jostins L 2012-11-01 Nature
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
| MAPPED |
0.482 |
0.0000002
(Vitamin B12)
|
|
0.143
(unit increase)
|
[NR] |
25147783
|
|
Keene KL 2014-08-06 Front Public Health
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.
|
| MAPPED |
0.47 |
0.0000000008
|
|
2.3
(% increase)
|
[1.80-2.90] |
22001757
|
|
Chambers JC 2011-10-16 Nat Genet
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
| MAPPED |
0.47 |
0.0000000000000001
|
|
0.031
(unit increase)
|
[NR] |
24097068
|
|
Willer CJ 2013-10-06 Nat Genet
Discovery and refinement of loci associated with lipid levels.
|
| MAPPED |
0.464 |
0.00000000000000000004
(SM-11 + 2 other traits)
|
|
0.129
(unit increase)
|
[NR] |
21886157
|
|
Suhre K 2011-08-31 Nature
Human metabolic individuality in biomedical and pharmaceutical research.
|
| MAPPED |
0.46 |
(CA19-9)
|
|
0.444
(U/ml increase)
|
[0.41-0.48] |
23300138
|
|
He M 2013-01-07 Gut
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
|
| MAPPED |
0.46 |
(CEA)
|
|
0.238
(ng/ml increase)
|
[0.21-0.26] |
23300138
|
|
He M 2013-01-07 Gut
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
|
| MAPPED |
0.44 |
0.000000000000002
(Plasma Vitamin B12)
|
|
0.07
(unit decrease)
|
[0.050-0.090] |
19744961
|
|
Hazra A 2009-09-10 Hum Mol Genet
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
|
| MAPPED |
0.431 |
0.00000002
|
|
|
|
20570966
|
|
McGovern DP 2010-06-22 Hum Mol Genet
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.
|
| MAPPED |
0.43 |
0.000000006
|
|
0.04
(unit increase)
|
[0.026-0.054] |
25028398
|
|
Weiss FU 2014-07-15 Gut
Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic pancreatitis: a genetic association study.
|
| MAPPED |
0.43 |
0.00000000003
(ADpSGEGDFXAEGGGVR)
|
|
0.041
(unit increase)
|
[0.029-0.053] |
24816252
|
|
Shin SY 2014-05-11 Nat Genet
An atlas of genetic influences on human blood metabolites.
|
| MAPPED |
0.43 |
0.000000000000001
|
|
1.8
(% increase)
|
[0.80-2.80] |
22001757
|
|
Chambers JC 2011-10-16 Nat Genet
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
| MAPPED |
0.43 |
0.00000000000000000002
(ADSGEGDFXAEGGGVR/ADpSGEGDFXAEGGGVR)
|
|
0.055
(unit decrease)
|
[0.043-0.067] |
24816252
|
|
Shin SY 2014-05-11 Nat Genet
An atlas of genetic influences on human blood metabolites.
|
| MAPPED |
0.272 |
0.000002
(Vitamin B12 )
|
|
0.03
(pmol/L increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|