CGGDB

> expression > dorso-rectal ganglion

Definition: "the ganglion that lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge. It contains 3 neuron cell bodies (DVA, DVB and DVC) that send their neuronal processes into the ventral nerve cord via dorso-rectal commissures that encircle the anus. The ganglion contains no local neuropil in the hermaphrodite. In the adult male tail, this ganglion gains additional neurons and some local neuropil. " [WBPaper:00038216]

JCEG ID

Family

Name

Locus Tag

Human Ortholog Name

OMIM

GWAS Catalog

JCEG083 ^* ⁼

GlcNAcT(GnT)

gly-12

F48E3.1

MGAT1

160995

STREAM	RAF	p-value	BETA	CI	Study
DOWNSTREAM	0.85	0.000006 (females)	0.16 (kg decrease)	[NR]	19851299
	Johansson A 2009-10-22 Obesity (Silver Spring) Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
DOWNSTREAM	0.85	0.00000007 (females)	2.96 (kg decrease)	[NR]	19851299
	Johansson A 2009-10-22 Obesity (Silver Spring) Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
MAPPED	0.47	0.000005 (HDL-C)	0.23 (mg/dL increase)	[NR]	19197348
	Lowe JK 2009-02-06 PLoS Genet Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
DOWNSTREAM	0.14	0.000008 (EA-glucose response)	3.67 (mg/dL increase)	[2.06-5.28]	23400010
	Del-Aguila JL 2013-02-12 Pharmacogenomics J Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

JCEG082 ^* ⁼

GlcNAcT(GnT)

gly-13

B0416.6

MGAT1

160995

STREAM	RAF	p-value	BETA	CI	Study
DOWNSTREAM	0.85	0.000006 (females)	0.16 (kg decrease)	[NR]	19851299
	Johansson A 2009-10-22 Obesity (Silver Spring) Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
DOWNSTREAM	0.85	0.00000007 (females)	2.96 (kg decrease)	[NR]	19851299
	Johansson A 2009-10-22 Obesity (Silver Spring) Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
MAPPED	0.47	0.000005 (HDL-C)	0.23 (mg/dL increase)	[NR]	19197348
	Lowe JK 2009-02-06 PLoS Genet Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
DOWNSTREAM	0.14	0.000008 (EA-glucose response)	3.67 (mg/dL increase)	[2.06-5.28]	23400010
	Del-Aguila JL 2013-02-12 Pharmacogenomics J Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

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