CGGDB

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Definition: "one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil" [ISBN:0-87969-307-X]

JCEG ID

Family

Name

Locus Tag

Human Ortholog Name

OMIM

GWAS Catalog

JCEG050 ^* ⁼

Fucosyltransferases

fut-1

K08F8.3

FUT5 FUT3 FUT4 FUT6

104230
111100
111100
136835
136836
602030
606865
613852

STREAM	RAF	p-value	BETA	CI	Study
DOWNSTREAM		0.000004 (EA)			22566498
	Turner ST 2012-05-07 Hypertension Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
DOWNSTREAM		0.0000009 (EA)	1.4 (unit increase)	[0.79-2.01]	22566498
	Turner ST 2012-05-07 Hypertension Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
MAPPED		0.00000003			24941225
	Liang Y 2014-06-18 PLoS One Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
MAPPED		0.0000000000004	49.78 (pg/ml increase)	[36.41-63.15]	22367966
	Lin X 2012-02-24 Hum Mol Genet Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.
MAPPED		0.0000000000000000008			24941225
	Liang Y 2014-06-18 PLoS One Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
MAPPED	0.38	(CA19-9)	0.282 (U/ml increase)	[0.20-0.37]	23300138
	He M 2013-01-07 Gut A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and Î± fetoprotein and their associations with cancer risk.
MAPPED	0.33	0.00000000000000000000000000000000001 (CEA)	0.073 (ng/ml increase)	[0.048-0.098]	23300138
	He M 2013-01-07 Gut A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and Î± fetoprotein and their associations with cancer risk.
MAPPED	0.33	(CA19-9)	0.481 (U/ml decrease)	[0.44-0.52]	23300138
	He M 2013-01-07 Gut A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and Î± fetoprotein and their associations with cancer risk.
MAPPED	0.2	0.00000000000000000000000000000000000000000000000000000002 (CA19-9)	0.169 (U/ml decrease)	[0.11-0.22]	23300138
	He M 2013-01-07 Gut A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and Î± fetoprotein and their associations with cancer risk.
MAPPED	0.11	0.0000000009 (DG12)	0.3 (unit decrease)	[0.20-0.40]	21203500
	Lauc G 2010-12-23 PLoS Genet Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
MAPPED	0.11	0.000000000003 (DG7)	0.34 (unit decrease)	[0.24-0.44]	21203500
	Lauc G 2010-12-23 PLoS Genet Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
MAPPED	0.11	0.000000000001 (FUC-A)	0.34 (unit decrease)	[0.24-0.44]	21203500
	Lauc G 2010-12-23 PLoS Genet Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
MAPPED	0.11	0.00000000000000004 (DG9)	0.41 (unit decrease)	[0.31-0.51]	21203500
	Lauc G 2010-12-23 PLoS Genet Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.

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