JCEG ID | JCEG123 | ||||||||
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Name | R08C7.4 WormBase | ||||||||
Human Ortholog |
OMIM:
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Family Name | Glyco_transf_92 | ||||||||
Locus Tag | R08C7.4 | ||||||||
RNAi phenotype |
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Sequence Features | |||||||||
Sequence | CDS |
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Protein |
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References |
Ceron J, Rual JF, Chandra A, Dupuy D, Vidal M, van den Heuvel S BMC Dev. Biol. (2007) 7 :30 [PMID : 17417969] Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. |
Functional Descriptions |
R08C7.4 none available |
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Deletion Mutants | ||||||||||||||||||
In Situ | ||||||||||||||||||
Expression |
Expression
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WBGene00019948 Phenotype Homology_paralog |
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Phenotype | Definition | RNAi / Allele | ||||||||||||||||
egg laying variant
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" Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control." [pmid:11813735, pmid:9697864, WB:cab] |
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embryonic lethal
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"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054] |
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growth rate variant
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"The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals." [GO:0040007, WB:WBPerson712] |
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protruding vulva
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"Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." [WB:WBPaper00004408, WB:WBPerson2021] |
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reduced brood size
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"The characteristic number of offspring produced is lower compared to that of control animals." [WB:WBPerson557] |
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sick
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"Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc." [WB:WBPaper00000179, WB:WBPaper00000565, WB:WBPerson712] |
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small
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"Animals are shorter and thinner than control animals at the same developmental stage." [WB:cab, WB:cgc31] |
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sterile
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"Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce." [GO:0000003, WB:WBPerson712] |
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