Japan Consortium for Glycobiology
and Glycotechnology DataBase

Actinomyces naeslundii

Stomatognathic Disease / Oral Infection

was caused by  Actinomyces naeslundii  (ATCC 12104)  Infections

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
47	Unclassfied Protein:Unknown	Dog small intestine Lc2 (lactosyl ceramide; lactocerebroside) Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR001961 [*]
47	Unclassfied Protein:Unknown	Human brain GM1 Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR002614 [*]
47	Unclassfied Protein:Unknown	Human meconium Lc4 (lactotetraosyl ceramide) Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR002827 [*]
47	Unclassfied Protein:Unknown	Human brain Asialo GM2 (GgO3; GA2; gangliotriaosylceramide ) GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR003580 [*]
47	Unclassfied Protein:Unknown	Frog brain Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR015645 [*]
47	Unclassfied Protein:Unknown	Human brain GD1b Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR024670 [*]
47	Unclassfied Protein:Unknown	Dog small intestine nLc4 (neolactotetraosyl ceramide; paragloboside) Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR026439 [*]
47	Unclassfied Protein:Unknown	Human erythrocytes GalNAc(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR026482 [*]
47	Unclassfied Protein:Unknown	Human erythrocytes Gb4 (globoside; globotetraose) GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR026907 [*]
47	Unclassfied Protein:Unknown	Vero cells SSEA-3 Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR026929 [*]
47	Unclassfied Protein:Unknown	Lc3 (lactotriaosyl ceramide; TriN) GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR027022 [*]
47	Unclassfied Protein:Unknown	Dog small intestine Gb3b (isoglobotriaosylceramide) Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR027164 [*]
47	Unclassfied Protein:Unknown	Rat colon carcinoma Isoglobotetraosyl ceramide (Isogloboside) GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR027175 [*]
47	Unclassfied Protein:Unknown	Mouse small intestine Asialo GM1 (GgO4; GA1; gangliotetraosylceramide) Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR027464 [*]
47	Unclassfied Protein:Unknown	Rat small intestine GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
47	Unclassfied Protein:Unknown	Dog small intestine Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)Glc(b1-1)Cer [ Not Binding ]
47	Unclassfied Protein:Unknown	Human erythrocytes Lc2 (lactosyl ceramide; lactocerebroside) Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR001961 [*]
47	Unclassfied Protein:Unknown	Human erythrocytes Gb3a (globotriaosylceramide; trihexosylceramide; Pk antigen; CTH) Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR002182 [*]
47	Unclassfied Protein:Unknown	Dog small intestine GalNAc(a1-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR002940 [*]
47	Unclassfied Protein:Unknown	Human meconium GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR003222 [*]
47	Unclassfied Protein:Unknown	Dog small intestine Gb5 (forssman glycolipid) GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR003244 [*]
47	Unclassfied Protein:Unknown	Human erythrocytes GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR005020 [*]
47	Unclassfied Protein:Unknown	Dog small intestine A6-2 GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR009061 [*]
47	Unclassfied Protein:Unknown	Various sources GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR011057 [*]
47	Unclassfied Protein:Unknown	Various sources Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR011255 [*]
47	Unclassfied Protein:Unknown	Various sources GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR011265 [*]
47	Unclassfied Protein:Unknown	Human meconium Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR011603 [*]
47	Unclassfied Protein:Unknown	Frog brain NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR014560 [*]
47	Unclassfied Protein:Unknown	Human kidney GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR015456 [*]
47	Unclassfied Protein:Unknown	Various sources Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR024624 [*]
47	Unclassfied Protein:Unknown	Human brain GD1a (disialoganglioside) NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR024659 [*]
47	Unclassfied Protein:Unknown	Mouse large intestine Fuc-Asialo GM1 (H-5-ganglio; Fuc-gangliotetraosyl ceramide/GgO4) Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR026492 [*]
47	Unclassfied Protein:Unknown	Human meconium Gb2 (galabiose; galabiosylceramide; digalactosylceramide) Gal(a1-4)Gal(b1-1)Cer [ Not Binding ] JCGG-STR026896 [*]
47	Unclassfied Protein:Unknown	Dog small intestine SSEA-1 (Lex; X-5) Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR027035 [*]
47	Unclassfied Protein:Unknown	Human erythrocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR027108 [*]
47	Unclassfied Protein:Unknown	Dog small intestine GalNAc(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ] JCGG-STR030510 [*]
47	Unclassfied Protein:Unknown	Most tissues Galactosyl ceramide (Galactocerebroside) Gal(b1-1)Cer [ Not Binding ] JCGG-STR031555 [*]
47	Unclassfied Protein:Unknown	Most tissues Glucosyl ceramide (CMH) Glc(b1-1)Cer [ Not Binding ] JCGG-STR031569 [*]
47	Unclassfied Protein:Unknown	Rat small intestine [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]

Stomatognathic Disease / Stomatitis

was caused by  Actinomyces naeslundii  (ATCC 12104/WVU45)  Infections

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
63	Lectin:Type-2 fimbrial lectins (130-kDa glycoprotein)	Polymorphonuclear leukocytes (PMNs) Gal [ Binding ]
63	Lectin:Type-2 fimbrial lectins (130-kDa glycoprotein)	Polymorphonuclear leukocytes (PMNs) Gal [ Binding ]
63	Lectin:Type-2 fimbrial lectins (130-kDa glycoprotein)	Polymorphonuclear leukocytes (PMNs) Gal(b1-3)GalNAc [ Binding ]
63	Lectin:Type-2 fimbrial lectins (130-kDa glycoprotein)	Polymorphonuclear leukocytes (PMNs) GalNAc [ Binding ]

Metabolism / Respiratory Burst

was caused by  Actinomyces naeslundii  (WVU45)  Infections

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
13	Adhesin:Adhesins	HL-60 promyelocytic leukemia cell line Asialo fetuin [ Binding ]
13	Adhesin:Adhesins	Human peripheral blood buffy coat cells PMN (polymorphonuclear leukocytes) surface glycoproteins in the absence of sialic acid [ Binding ]
13	Adhesin:Adhesins	HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) Gal [ Binding ]
13	Adhesin:Adhesins	HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) GalNAc [ Binding ]
56	Lectin:Type-2 fimbrial lectins	GM1 Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR002614 [*]
56	Lectin:Type-2 fimbrial lectins	GT1b (trisialoganglioside) NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR005131 [*]
56	Lectin:Type-2 fimbrial lectins	GD1a (disialoganglioside) NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR024659 [*]
56	Lectin:Type-2 fimbrial lectins	GD1b Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR024670 [*]
56	Lectin:Type-2 fimbrial lectins	Gb4 (globoside; globotetraose) GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR026907 [*]
56	Lectin:Type-2 fimbrial lectins	Asialo GM1 (GgO4; GA1; gangliotetraosylceramide) Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer [ Binding ] JCGG-STR027464 [*]

  Actinomyces naeslundii  (genospecies1; B-2-G/B-1-L)

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Buccae [beta]-linked galactosamine GalNAc(b 2:1 [ Binding ]
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Buccae [beta]-linked galactosamine GalNAc(b 2:2 [ Not Binding ]

  Actinomyces naeslundii  (genospecies1; P-4-N/Pn-1-GA/Pn-22-E/P-5-L/P-10-A)

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Plaque [beta]-linked galactosamine GalNAc(b 2:1 [ Binding ]
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Plaque [beta]-linked galactosamine GalNAc(b 2:2 [ Not Binding ]

  Actinomyces naeslundii  (genospecies2; B-3-N/B-10-N/B-3-K/B-10-K/B-1-G/B-3-L/B-10-L/B-1-A)

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
90	Fimbria:Type 1-fimbriae Genomic Name:fimP	Buccae APRPs (acidic proline-rich proteins) [ Binding ]
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Buccae [beta]-linked galactosamine GalNAc(b 2:2 [ Binding ]
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Buccae [beta]-linked galactosamine GalNAc(b 2:1 [ Not Binding ]

  Actinomyces naeslundii  (genospecies2; P-1-N/P-6-K/P-1-G/P-1-L/P-1-A)

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
90	Fimbria:Type 1-fimbriae Genomic Name:fimP	Plaque APRPs (acidic proline-rich proteins) [ Binding ]
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Plaque [beta]-linked galactosamine GalNAc(b 2:2 [ Binding ]
90	Fimbria:Type 2-fimbriae Genomic Name:fimA	Plaque [beta]-linked galactosamine GalNAc(b 2:1 [ Not Binding ]

  Actinomyces naeslundii  

PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
25	Unclassfied Protein:Unknown	Gal(b1-3)GalNAc [ Binding ]
25	Unclassfied Protein:Unknown	GalNAc(b1-3)Gal [ Binding ]
50	Fimbria:Type 2-fimbriae	Gal(b1-4)Glc [ Binding ]