JCEG ID JCEG222
Name gly-10      WormBase    NCBI Gene
Human Ortholog

GGDB:GALNT10 

OMIM: 608043 615138

OrthoList :   GALNTL6   GALNT10  (Ensembl Compara)

GWAS Catalog
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 0.58 0.00000005 0.03 (unit increase) [0.02-0.04] 25231870
DOWNSTREAM 0.42 0.00000000000005 0.021 (unit increase) [0.012-0.030] 23583978
MAPPED 0.379 0.00000003 1.0615711 [1.04-1.08] 25056061
GGDB Score E-val
GALNT10 528 e-152
GALNT1 396 e-112
GALNT13 390 e-110
GALNT7 365 e-102
GALNT4 325 1e-90
GALNT11 318 2e-88
GALNT5 317 3e-88
GALNT14 308 2e-85
GALNT3 302 1e-83
GALNT2 300 5e-83
GALNT6 298 1e-82
GALNT12 285 2e-78
GALNT15 279 9e-77
GALNT19 279 1e-76
GALNT9 268 3e-73
GALNT8 244 2e-66
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
Family Name ppGalNAcT
Locus Tag Y45F10D.3
RNAi phenotype
phenotype WT
Microscope observation (Image)
COPAS (Image)

Normal

hsp-4::GFP (Image)
Sequence Features
Sequence CDS
Protein
References

Wang H, Spang A, Sullivan MA, Hryhorenko J, Hagen FK Mol. Biol. Cell (2005) 16 (9) :4202-13 [PMID : 15987734] The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation.

Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation.

Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs.

Bennett EP, Mandel U, Clausen H, Gerken TA, Fritz TA, Tabak LA Glycobiology (2012) 22 (6) :736-56 [PMID : 22183981] Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.

WormBase (WS254)

Functional Descriptions gly-10
Deletion Mutants ok2439 gk351 ok2217
In Situ clone=511a6   
Expression Expression

WBGene00001635
Phenotype
Homology_paralog
Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele


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