JCEG ID | JCEG218 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Name | gly-9 WormBase NCBI Gene | |||||||||||||||||||||||||||||||||||||||||||||||||||
Human Ortholog |
GGDB:GALNT1 OMIM: OrthoList : GALNT5 (Ensembl Compara)
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Family Name | ppGalNAcT | |||||||||||||||||||||||||||||||||||||||||||||||||||
Locus Tag | Y47D3A.23 | |||||||||||||||||||||||||||||||||||||||||||||||||||
RNAi phenotype |
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Sequence Features | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence | CDS |
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Protein |
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References |
Hagen FK, Nehrke K J. Biol. Chem. (1998) 273 (14) :8268-77 [PMID : 9525933] cDNA cloning and expression of a family of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase sequence homologs from Caenorhabditis elegans. Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schafer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H J. Biol. Chem. (2002) 277 (25) :22623-38 [PMID : 11925450] Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila. Wang H, Spang A, Sullivan MA, Hryhorenko J, Hagen FK Mol. Biol. Cell (2005) 16 (9) :4202-13 [PMID : 15987734] The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation. Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation. Berndt JD, Aoyagi A, Yang P, Anastas JN, Tang L, Moon RT J. Cell Biol. (2011) 194 (5) :737-50 [PMID : 21875946] Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling. Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs. |
Functional Descriptions |
gly-9 |
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Deletion Mutants | gk440 | |||||||||||||||||
In Situ | clone=163c10 | |||||||||||||||||
Expression |
Expression
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WBGene00012934 Phenotype Homology_paralog |
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Phenotype | Definition | RNAi / Allele | ||||||||||||||||
bivulva
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"Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development." [WB:WBPaper00040151, WB:WBPerson712] |
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