JCEG ID JCEG194
Name gly-19      WormBase    NCBI Gene
Human Ortholog

GGDB:GCNT3 

OMIM:

OrthoList :   GCNT7   GCNT4   GCNT2   GCNT3   GCNT1   GCNT6  (Ensembl Compara)

GGDB Score E-val
GCNT1 125 9e-31
GCNT3 125 2e-30
GCNT2 117 3e-28
GCNT2 111 2e-26
GCNT2 109 1e-25
GCNT4 106 6e-25
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
Family Name b6GnT
Locus Tag F22D6.12
RNAi phenotype
phenotype WT
Microscope observation (Image)
COPAS (Image)

Normal

hsp-4::GFP (Image)
Sequence Features kr:Detected
tm:Detected
dxd:GVD/DEG
gg_motif:M1, M2, M3, M4, M5
Sequence CDS
Protein
References

Warren CE, Krizus A, Dennis JW Glycobiology (2001) 11 (11) :979-88 [PMID : 11744632] Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues.

Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation.

Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs.

WormBase (WS254)

Functional Descriptions gly-19

gly-19 encodes a 2/I N-acetylglucosaminyltransferase; a gly-19::gfp promoter fusion is expressed in the intestine and in the anal sphincter muscle from embryogensis through adulthood.
Deletion Mutants
In Situ In Situ   
Expression Expression
db_name wbbt name def reliability expr_pattern paper WormAtlas
WB WBbt:0005772

intestine "A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] Certain WB:Expr1787 WBPaper00005030 WormAtlas
WB WBbt:0005772

intestine "A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] Enriched WBPaper00037950 : intestine_CoreEnriched, intestine_embryo_enriched, intestine_larva_enriched
 WBPaper00037950 WormAtlas
WB WBbt:0005772

intestine "A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] Enriched WBPaper00040985 : AIN-2_L4_intestine
 WBPaper00040985 WormAtlas
WB WBbt:0005798

anal sphincter muscle "a saddle-shaped muscle cell that encircles the intestinal-rectal valve" [WB:rynl, WBPaper:00038216] Certain WB:Expr1787 WBPaper00005030 WormAtlas

WBGene00001644
Phenotype
Homology_paralog
Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele


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