| JCEG ID |
JCEG190 |
| Name |
ZK1225.5
WormBase
NCBI Gene
|
| Human Ortholog |
GGDB:GCNT1
OMIM:
GWAS Catalog
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.71 |
0.000007
|
1.56
|
|
[1.28-1.89] |
21546767
|
|
Murea M 2011-05-05 Am J Nephrol
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.
|
|
| Family Name |
b6GnT |
| Locus Tag |
ZK1225.5
|
| RNAi phenotype |
|
phenotype
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|
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Microscope observation (Image)
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COPAS (Image)
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hsp-4::GFP (Image)
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| Sequence Features |
tm:soluble
dxd:NFD/
gg_motif:M1, M2, M4
|
| Sequence |
CDS
atgaaatttattcaacttgcgctgttctttcttattggaatatcaactac
ggatacatcgaacaagactcaacaaattttcaagaaaattggaaaacgat
tctcgctgagtgaacatggattaatccaacggtttaagttttattggaag
actcaggaggatgtggatgctgcaagaaatcattcggctcaattggtggc
tcttcacttgttgagacaatcatcgaatcacaattataagtttcaagaga
gtgctgatattttgtatagtctgatggatataaacttcgagggaaagata
tgcggtggaatggaaatgctgaatttctatcaaatggctgaattctggaa
acgacaacgagggacgtaccggagaaattctggagagaaagtttcctgga
gtcctgttccaacggagagtataaatgacaatatattcctggtatcgttt
atggcacattccacttgggagtactcttcaaagatatcttatcttgttaa
aatggaacttctcggagaaaaaccatacagcaactacacactgacaagga
ttgaagaagttggagcatgtacagagtatggtgttacgaatctggaaaac
actgatatatttttggatcttcatgaaactgacccagagagagttgatac
aaggaaaaaagtattcaaacatttctatgaactattcacaatggatagag
aagagtctgtaatcccatttaattggctatcttataccggtgtatctgct
gatctcgacattcaagtgtgtcacgggagtgagttgaagaaaatcggaaa
gtataattttatcgattggtggctctggttccagaagatgtatcatccgg
tgaaaggcgatcaacacacagcggtgcaattgactggtggagagtacgat
cgatttgtattcagagtaactatgagagttcaaattggtactttaataga
taacccagttgaggaattcaacttcaagattcaagttagatataatgttt
atggcgacaaagaatggaatattgataagttcgaagtgatgtgcccatta
gttgcagttccagagattgatttgatgaagaagcacgcaatcgcttttaa
ccaggttattggagcaagaattcaaaagatggttgacgccccagagatgt
ggtatacagcagttgatgctcttacaacattgactagccggaagtttgaa
attagaaattgtgcagggctcaatggagagacaatggagaaggctaacaa
ttttgcggatctgacgcacaaattctgggagctgaacaaatctacaaacg
gacggatggaaggatacgacttgggtggaatcagtgaattctcagaaatt
tcggagaaagtatggttgtacatattcatcatttggacaccacaacctga
aatacttgtgcaccaatcgcaatggacatttggcttagaatggaatagtg
atttacaagctttttcgattttttcaatgatactgagatgtccgaaaaat
gggaaagaaagaaaacgttttattacacttcattaa
|
Protein
MKFIQLALFFLIGISTTDTSNKTQQIFKKIGKRFSLSEHGLIQRFKFYWKTQEDVDAARN
HSAQLVALHLLRQSSNHNYKFQESADILYSLMDINFEGKICGGMEMLNFYQMAEFWKRQR
GTYRRNSGEKVSWSPVPTESINDNIFLVSFMAHSTWEYSSKISYLVKMELLGEKPYSNYT
LTRIEEVGACTEYGVTNLENTDIFLDLHETDPERVDTRKKVFKHFYELFTMDREESVIPF
NWLSYTGVSADLDIQVCHGSELKKIGKYNFIDWWLWFQKMYHPVKGDQHTAVQLTGGEYD
RFVFRVTMRVQIGTLIDNPVEEFNFKIQVRYNVYGDKEWNIDKFEVMCPLVAVPEIDLMK
KHAIAFNQVIGARIQKMVDAPEMWYTAVDALTTLTSRKFEIRNCAGLNGETMEKANNFAD
LTHKFWELNKSTNGRMEGYDLGGISEFSEISEKVWLYIFIIWTPQPEILVHQSQWTFGLE
WNSDLQAFSIFSMILRCPKNGKERKRFITLH
|
| References |
|
| Functional Descriptions |
ZK1225.5
none available
|
| Deletion Mutants |
|
| In Situ |
In Situ
|
| Expression |
Expression
|
WBGene00014239
Phenotype
Homology_paralog
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| Phenotype |
Definition |
RNAi / Allele |
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embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
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larval arrest
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"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
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larval lethal
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"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
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lethal
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"Animals die prematurely at any stage of the life cycle." [WB:WBPaper00001109, WB:WBPerson2021]
|
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maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
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organism morphology variant
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"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
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postembryonic development variant
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"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
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slow growth
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"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
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sterile progeny
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"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
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Variant
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"Animals exhibit variations compared to a given control." [WB:WBPerson557]
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