| JCEG ID |
JCEG075 |
| Name |
F17C11.7
WormBase
|
| Human Ortholog |
GGDB:PIGT
OMIM:
610272
615398
615399
OrthoList :
PIGT
(Ensembl Compara)
|
| Family Name |
GPI-anchor synthesis |
| Locus Tag |
F17C11.7
|
| RNAi phenotype |
|
phenotype
|
|
|
Microscope observation (Image)
|
|
|
COPAS (Image)
|
|
|
hsp-4::GFP (Image)
|
|
|
| Sequence Features |
|
| Sequence |
CDS
ATGCGGATACTAACTTCTTATCTGCTGTTATCAATACTTTCATCATGCCATGGGCTTAGC
GAGAATTTCGATGAAAAATTGACATTATCTCCAGTTAGTAAAAACGAGCTACGTGTTGAT
TTTAGGTTTAATTCCGAGAGAGAATTCAACAGGAAAACAGAATCTGGCGATTATCTAACA
TTCCCACGTATTATTCAAGAACTTCTCTCTCGTTATTCAGTTCGAAAATTGACTGTAACG
ATGGCTCACGGACGTTGGAATTTAATTGGATGGGGACTTCCACCTCAACCGTCTTCTCCA
ACTGGAGCTCAAGTTTTTGCAGAATTTGAAGCTGACCAACAAGAAGATGCCGATGAACGA
ATGAAATTTTTGGTAGAAGCTTTAAATGGAGTTCTATGTACATCTATATCACATATCAAT
GTTATCACGAGCCCAGAATTTATAGTTCTCAAAAACCATGGAGGAGAAACAAGTGTTCAT
AAAAGATATGGTGTTCTGAGTGGTGAGACTACATGTACTGAAAACTTGACCAGACTCCGG
AAGCTATTAGCTTGTAAAGAGAATGGTATCAGTACATTGCTTCATCCATCCAAACTATAC
AACTCGGTGTATCATTCATCCCATCTCGTTGTGGAGCAACAATGTGACAAAGATCAATGC
AACTCGAAAATGGAAGTAGGAGTATCTGTTGTTATGCGTAACCCGTCTCAAAAAACTCAA
CGTCACTGGTCTCTGGCTGATGTGTTCGAACGAAAACTCGGATCGCAATGTAAAGTTGCT
CGTAGTAGTAAAATACATGTTATTGGTACTACTGGAGAGATAACCACGACTGATGTGAAA
AATCTAACAACAATCAATGGAGAAGAACCATTCGAATTATATATTCCAATAACTGATATT
TCGATGAAACAATCAGTTGTGAAAGCGTGGTCTTCTCAGGGAGGATTCGAGCAGAAACAT
GGAGTTTTGACTGTACACATTACAAATGACGAATCAGCTTCGGAAATTCATGTATCACAA
ATTATTCCATATTATGTTCATTTACGTTACAGTAAAATCAACTGGAAATGTGATAAAAAT
GGTGTTCCCCGTATTGAGAAGATCTTCAAGAATAGCAAAAGCTTGGAGGCGCCTACACTA
CTACAGTACAAAATGAAACTTTCTGCAGGACAGACTTGTGAACTTACTATTCCATTTGAT
AAGCAACTTTTGAGACTAGAACAATACCCACCAGATGCAAATCATGGAATGCATATTCCA
GCAGCAAGTGTCTACATTCAAAAGAGCACCTCAACATACACAATTCATTCGAATGCCATC
TTGGTCCTTCTACCAGTCCCCGATTTCTCAATGCCATTCAATGTGATTTGTTTCGTTGCC
ACCGCTTTTGCTCTAGTCTTCGGACCAATTCAACTTTATTCAACACTTTGGTTGGCACCG
GTCGTCAAAAAGTCACAATGGGGGCGGAAAATTCATCGGGCGATTCTTTTGGCTATCATT
GCATTCTGCCTATATGCTCATATGATGGATATCAATTTGAACGAAATTCGACGTGGTATC
GAAACATATTTTGAAAAGCTCAACGAACTTAAGTGA
ATGCGGATACTAACTTCTTATCTGCTGTTATCAATACTTTCATCATGCCATGGGCTTAGC
GAGAATTTCGATGAAAAATTGACATTATCTCCAGTTAGTAAAAACGAGCTACGTGTTGAT
TTTAGGTTTAATTCCGAGAGAGAATTCAACAGGAAAACAGAATCTGGCGATTATCTAACA
TTCCCACGTATTATTCAAGAACTTCTCTCTCGTTATTCAGTTCGAAAATTGACTGTAACG
ATGGCTCACGGACGTTGGAATTTAATTGGATGGGGACTTCCACCTCAACCGTCTTCTCCA
ACTGGAGCTCAAGTTTTTGCAGAATTTGAAGCTGACCAACAAGAAGATGCCGATGAACGA
ATGAAATTTTTGGTAGAAGCTTTAAATGGAGTTCTATTTCTCAAAAACCATGGAGGAGAA
ACAAGTGTTCATAAAAGATATGGTGTTCTGAGTGGTGAGACTACATGTACTGAAAACTTG
ACCAGACTCCGGAAGCTATTAGCTTGTAAAGAGAATGGTATCAGTACATTGCTTCATCCA
TCCAAACTATACAACTCGGTGTATCATTCATCCCATCTCGTTGTGGAGCAACAATGTGAC
AAAGATCAATGCAACTCGAAAATGGAAGTAGGAGTATCTGTTGTTATGCGTAACCCGTCT
CAAAAAACTCAACGTCACTGGTCTCTGGCTGATGTGTTCGAACGAAAACTCGGATCGCAA
TGTAAAGTTGCTCGTAGTAGTAAAATACATGTTATTGGTACTACTGGAGAGATAACCACG
ACTGATGTGAAAAATCTAACAACAATCAATGGAGAAGAACCATTCGAATTATATATTCCA
ATAACTGATATTTCGATGAAACAATCAGTTGTGAAAGCGTGGTCTTCTCAGGGAGGATTC
GAGCAGAAACATGGAGTTTTGACTGTACACATTACAAATGACGAATCAGCTTCGGAAATT
CATGTATCACAAATTATTCCATATTATGTTCATTTACGTTACAGTAAAATCAACTGGAAA
TGTGATAAAAATGGTGTTCCCCGTATTGAGAAGATCTTCAAGAATAGCAAAAGCTTGGAG
GCGCCTACACTACTACAGTACAAAATGAAACTTTCTGCAGGACAGACTTGTGAACTTACT
ATTCCATTTGATAAGCAACTTTTGAGACTAGAACAATACCCACCAGATGCAAATCATGGA
ATGCATATTCCAGCAGCAAGTGTCTACATTCAAAAGAGCACCTCAACATACACAATTCAT
TCGAATGCCATCTTGGTCCTTCTACCAGTCCCCGATTTCTCAATGCCATTCAATGTGATT
TGTTTCGTTGCCACCGCTTTTGCTCTAGTCTTCGGACCAATTCAACTTTATTCAACACTT
TGGTTGGCACCGGTCGTCAAAAAGTCACAATGGGGGCGGAAAATTCATCGGGCGATTCTT
TTGGCTATCATTGCATTCTGCCTATATGCTCATATGATGGATATCAATTTGAACGAAATT
CGACGTGGTATCGAAACATATTTTGAAAAGCTCAACGAACTTAAGTGA
|
Protein
MRILTSYLLLSILSSCHGLSENFDEKLTLSPVSKNELRVDFRFNSEREFNRKTESGDYLT
FPRIIQELLSRYSVRKLTVTMAHGRWNLIGWGLPPQPSSPTGAQVFAEFEADQQEDADER
MKFLVEALNGVLCTSISHINVITSPEFIVLKNHGGETSVHKRYGVLSGETTCTENLTRLR
KLLACKENGISTLLHPSKLYNSVYHSSHLVVEQQCDKDQCNSKMEVGVSVVMRNPSQKTQ
RHWSLADVFERKLGSQCKVARSSKIHVIGTTGEITTTDVKNLTTINGEEPFELYIPITDI
SMKQSVVKAWSSQGGFEQKHGVLTVHITNDESASEIHVSQIIPYYVHLRYSKINWKCDKN
GVPRIEKIFKNSKSLEAPTLLQYKMKLSAGQTCELTIPFDKQLLRLEQYPPDANHGMHIP
AASVYIQKSTSTYTIHSNAILVLLPVPDFSMPFNVICFVATAFALVFGPIQLYSTLWLAP
VVKKSQWGRKIHRAILLAIIAFCLYAHMMDINLNEIRRGIETYFEKLNELK
MRILTSYLLLSILSSCHGLSENFDEKLTLSPVSKNELRVDFRFNSEREFNRKTESGDYLT
FPRIIQELLSRYSVRKLTVTMAHGRWNLIGWGLPPQPSSPTGAQVFAEFEADQQEDADER
MKFLVEALNGVLFLKNHGGETSVHKRYGVLSGETTCTENLTRLRKLLACKENGISTLLHP
SKLYNSVYHSSHLVVEQQCDKDQCNSKMEVGVSVVMRNPSQKTQRHWSLADVFERKLGSQ
CKVARSSKIHVIGTTGEITTTDVKNLTTINGEEPFELYIPITDISMKQSVVKAWSSQGGF
EQKHGVLTVHITNDESASEIHVSQIIPYYVHLRYSKINWKCDKNGVPRIEKIFKNSKSLE
APTLLQYKMKLSAGQTCELTIPFDKQLLRLEQYPPDANHGMHIPAASVYIQKSTSTYTIH
SNAILVLLPVPDFSMPFNVICFVATAFALVFGPIQLYSTLWLAPVVKKSQWGRKIHRAIL
LAIIAFCLYAHMMDINLNEIRRGIETYFEKLNELK
|
| References |
Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PV, Kamath RS, Fraser AG, Ahringer J, Plasterk RH
PLoS Biol.
(2003)
1
(1)
:E12
[PMID : 14551910]
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions.
|
| Functional Descriptions |
F17C11.7
none available
|
| Deletion Mutants |
|
| In Situ |
|
| Expression |
Expression
| db_name |
wbbt |
name |
def |
reliability |
expr_pattern |
paper |
WormAtlas |
| WB |
WBbt:0005784
|
germ line |
"cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes." [ISBN:0140512888] |
Enriched |
WBPaper00044760 : germline_specific
|
WBPaper00044760
|
|
|
WBGene00008918
Phenotype
Homology_paralog
|
|
|
| Phenotype |
Definition |
RNAi / Allele |
|
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
|
lethal
|
"Animals die prematurely at any stage of the life cycle." [WB:WBPaper00001109, WB:WBPerson2021]
|
|
long
|
"Animals are longer than control animals at the same developmental stage." [WB:cab, WB:cgc31]
|
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
thin
|
"Animals exhibit a reduced girth compared to a control animal of the same developmental stage." [WB:WBPerson712]
|
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|
