| JCEG ID |
JCEG021 |
| Name |
T09E11.6
WormBase
NCBI Gene
|
| Human Ortholog |
GGDB:C1GALT1
OMIM:
OrthoList :
GCNT7
GCNT4
GCNT2
GCNT3
GCNT1
GCNT6
(Ensembl Compara)
GWAS Catalog
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.0000002
(PCB105)
|
|
1.32
(unit decrease)
|
[0.83-1.81] |
25839716
|
|
Ng E 2015-04-02 Environ Res
Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample.
|
| MAPPED |
0.46 |
0.000004
|
|
|
[NR] |
19010793
|
|
Baranzini SE 2008-11-14 Hum Mol Genet
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
|
| MAPPED |
0.444 |
0.000001
|
|
0.099
(unit decrease)
|
[0.06-0.138] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
| MAPPED |
0.444 |
0.0000006
|
|
0.101
(unit increase)
|
[0.062-0.14] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
|
| Family Name |
Core 1 GalT |
| Locus Tag |
T09E11.6
|
| RNAi phenotype |
|
phenotype
|
|
|
Microscope observation (Image)
|
|
|
COPAS (Image)
|
Normal
|
|
hsp-4::GFP (Image)
|
|
|
| Sequence Features |
tm:Detected
dxd:DDD
kr:Detected
gg_motif:M1,M3,M4,M6
|
| Sequence |
CDS
atgtcgaacattctttacattttgattaaaaacttcctttcgtcaaaatc
atctttaaaccgatggctgctattgattattgctgcaagtttcatatcat
actttttagtaattctactggaagaaaaagaagagccttaccaaactctt
tcggagtccactctgtcaaactgtgaacaaggtcctaccaagcaagacct
tcatcgtcaccatacagatattgctgatgtgtaccgggaacgaggttttg
ctgatgataagcgaggatcataccgtcgtcggccggagaccgctcatgtt
gattgtggtcgaattctagctggtgataagccttatcttcaatcactcac
tggaacaaatcgcgttaaaatagtggaaaactgtaatctaaacatgtcct
gtaaagcaattaggagcaggattcttccatcaaacgataatattctgaga
cctttgaagcatggaatcgcatttgctagaattgtgtacaaggactatga
atttattgaaaagcaggtgcaagtgtcttttcatcctcagaatgcatttt
gttttgtgattgatataaatgcatcagaggaatttaagaagcggatgaga
gccctggctgcgtgtatgccaaatgtcatagtgctcgctgacgaggatcc
tgtctactcttctggtcacaatgtcaacctggttcacaacaaatgtctca
aagccctactcgacatacctggctggaactacgctttgctacttcaaaat
cacgatcttataatgaaatctgtgtatgagatggagcaaatcttcgagtg
gctcgggggagcgaacgatatttttgtgactcacgaaattggtcgagtcg
atgtgaaaaagctgaagtgggatccaatgtcgctaaaattgtttataaat
gaaactgaaatggacaagttattactgacaactcctatgaaaattgtgaa
aggatgggttcactgttccttgtcgagagcgtcagttgagtggatgtttc
agaaacttgatccatcaatttttatgcatcaattgaaccagggtagatat
ggagttgatgagcagtattttcctatccttcaggccaatgcagagttcgg
aatgcctggacactttaccgatgagtgcctgcagcaaggaaaaactacag
agttcataacaagaattgccttatgggtgcccgaaagcaagtgtgacacg
aatatgactcgtcatgcagtctgcatcattggtctagagcacttccaagc
cgttgcgtcgtttacacatttgatgttcaataaagtgattccatcatttg
ataattcaatcgtagagtgtaccgccgagctcctgcacaatcgaacattc
ttggggcaagttgaccatccgttgaaagaagattattacaaaaacatggt
caatgttctttaccacaaacaccacttggaaccgggttacaagctgaact
gcacaccacgttacagcgagctgtggaaggaataa
|
Protein
MSNILYILIKNFLSSKSSLNRWLLLIIAASFISYFLVILLEEKEEPYQTLSESTLSNCEQ
GPTKQDLHRHHTDIADVYRERGFADDKRGSYRRRPETAHVDCGRILAGDKPYLQSLTGTN
RVKIVENCNLNMSCKAIRSRILPSNDNILRPLKHGIAFARIVYKDYEFIEKQVQVSFHPQ
NAFCFVIDINASEEFKKRMRALAACMPNVIVLADEDPVYSSGHNVNLVHNKCLKALLDIP
GWNYALLLQNHDLIMKSVYEMEQIFEWLGGANDIFVTHEIGRVDVKKLKWDPMSLKLFIN
ETEMDKLLLTTPMKIVKGWVHCSLSRASVEWMFQKLDPSIFMHQLNQGRYGVDEQYFPIL
QANAEFGMPGHFTDECLQQGKTTEFITRIALWVPESKCDTNMTRHAVCIIGLEHFQAVAS
FTHLMFNKVIPSFDNSIVECTAELLHNRTFLGQVDHPLKEDYYKNMVNVLYHKHHLEPGY
KLNCTPRYSELWKE
|
| References |
|
| Functional Descriptions |
T09E11.6
none available
|
| Deletion Mutants |
|
| In Situ |
|
| Expression |
Expression
|
WBGene00011655
Phenotype
Homology_paralog
|
|
|
| Phenotype |
Definition |
RNAi / Allele |
|
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|