JCEG ID |
JCEG009 |
Name |
C08H9.3
WormBase
NCBI Gene
|
Human Ortholog |
GGDB:ALG8
OMIM:
608103
608104
OrthoList :
ALG8
(Ensembl Compara)
GGDB |
Score |
E-val |
ALG8
|
247 |
6e-67 |
ALG6
|
76 |
2e-15 |
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
|
Family Name |
Asparagine-linked glycosylation (ALG) genes |
Locus Tag |
C08H9.3
|
RNAi phenotype |
phenotype
|
WT
|
Microscope observation (Image)
|
|
COPAS (Image)
|
Normal
|
hsp-4::GFP (Image)
|
Normal
|
|
Sequence Features |
kr:N.D.
tm:Detected
|
Sequence |
CDS
atgggcgaagtgcagctggtcctggctgtgacagcgatcctaatatcctt caaatgtttgctgattcctgcttatgtatctacagatttcgaggttcatc gtaattggatggctgtgacgtggcaacggccattgtgtgaatggtataca gaagcaacatctgaatggacactcgattatcctccgtttttcgcatattt cgaattgggtcttgcgtctgttgcgcacttttttggattcgatgaatgtt tggtgatatcaaagactccgcggttttctcgacgaattttgattttccag cgattttcagtaattttctgcgatattttgtatattgctgtctgcgctct atactccttccgctctccacgtctagtcagcagaattccgaagaaattgc aacaaaatggacgagaagcttgtttcgtgcttctggcatcattacaagcc ttaattatttgtgattcaattcattttcaatacaattcgatgctcactgc gatttttttgatgtctctgttttttatcgatacggaaagatatctgatgg cagcactttcctactcaattttgctgaatttcaagcacatctacgtctat tacgccctcggatacgttttctactatttagtcaattattttcaattctc tggaaatgttcttctggccaatacgccaaaagcaatttctctcgccattg ctctgctcattccattttgtgcatcaattttcccatttatccacgcctca ggagtccagggccttcaaaatattgccacccgcctctttccggtatcgcg aggcctaacacacgcctactgggcgcctaatttttgggctctgtacaatt tcgcagacttatgcctgtatagagttttaagtttgctcaagatcggaaag tttgatgctccgacatatacgtctggtctggttcaggaatattcgcacag tgtcctaccaaatgtatcacccatgggaacactctgccttgttgtcatct cctcaatgatagttctcactgggttggtgattcgtaggaaagattctgcc gatttctcgttgttcgccgtcttttccgccttctgcttcttctatttcgg atatcacgtccacgaaaaggcgataatcctggttacggtaccaatgaccg tattcgcgattaagaatccaaaataccattcaattctgatccacctcaca tgcatcgcctcgttctcactatttccactgctattcacacctttcgaaac acttctgaaatatgcgatttgtgtgtcgtacttcttcatacagctggtgt tcctaaaacgcgtcacacttatgccactttcggatttgatacctacaaga cacgttgcaagctggttactaatggggatggtggaggtgtataacacatt tttgcacaagtggctctggacgtctcgccttccatttgcccctctcatgg cgatatcaatactcaccgctatcgagcttaccggactgataggtgctctt atctggagcacatttggagatggaatattcgaaatttggtgggcaaaagc cacttgtcagattcgcgagcgtcttatccgcgattcaacatactctgtac aagctgtggaggacttggacgatgtgaagttggttgctggaattgataca tcggcggctaaactaaattctgatatggtttatattagtgtcagtttttg gacgtatccagatcttaaacacgtggcaaccatttctgacaccaggatgc tcgaactaccgtatatcccacaatacttggcagttagagaagcagaagtt atggctgatttcctgaaaagtgtgatcacagagcgtccagagctccgacc ggatgtgattttgtgtgacggatttggagagtttcattcaagaggttgtg gaatggcttgtcacgtgggagctctttccggaattgccagcattggtgtt gccaaaaatttgactcttcaccacacttatgaaactattggcatggaaaa caaatcgaaagttgacagttttgtggaacattgccgagaggtctataaaa acaataaaacatcgcctggatttatcccatttgatatcgttgagccggtg gtgttgaacattctaagaatgggtagttcaatgaacggagtattcgtctc tgcgggttacggtatcgacttggaactgtccactgaaatttgctcacaac ttttgctcaacaacacgacgattgagccaattcgagctgccgatctagag tctagacgtcttgttcgagagaatttcgatgggaatgagaaacttgaata a
atgggcgaagtgcagctggtcctggctgtgacagcgatcctaatatcctt caaatgtttgctgattcctgcttatgtatctacagatttcgaggttcatc gtaattggatggctgtgacgtggcaacggccattgtgtgaatggtataca gaagcaacatctgaatggacactcgattatcctccgtttttcgcatattt cgaattgggtcttgcgtctgttgcgcacttttttggattcgatgaatgtt tggtgatatcaaagactccgcggttttctcgacgaattttgattttccag cgattttcagtaattttctgcgatattttattgctgtctgcgctctatac tccttccgctctccacgtctag
|
Protein
MGEVQLVLAVTAILISFKCLLIPAYVSTDFEVHRNWMAVTWQRPLCEWYTEATSEWTLDY PPFFAYFELGLASVAHFFGFDECLVISKTPRFSRRILIFQRFSVIFCDILYIAVCALYSF RSPRLVSRIPKKLQQNGREACFVLLASLQALIICDSIHFQYNSMLTAIFLMSLFFIDTER YLMAALSYSILLNFKHIYVYYALGYVFYYLVNYFQFSGNVLLANTPKAISLAIALLIPFC ASIFPFIHASGVQGLQNIATRLFPVSRGLTHAYWAPNFWALYNFADLCLYRVLSLLKIGK FDAPTYTSGLVQEYSHSVLPNVSPMGTLCLVVISSMIVLTGLVIRRKDSADFSLFAVFSA FCFFYFGYHVHEKAIILVTVPMTVFAIKNPKYHSILIHLTCIASFSLFPLLFTPFETLLK YAICVSYFFIQLVFLKRVTLMPLSDLIPTRHVASWLLMGMVEVYNTFLHKWLWTSRLPFA PLMAISILTAIELTGLIGALIWSTFGDGIFEIWWAKATCQIRERLIRDSTYSVQAVEDLD DVKLVAGIDTSAAKLNSDMVYISVSFWTYPDLKHVATISDTRMLELPYIPQYLAVREAEV MADFLKSVITERPELRPDVILCDGFGEFHSRGCGMACHVGALSGIASIGVAKNLTLHHTY ETIGMENKSKVDSFVEHCREVYKNNKTSPGFIPFDIVEPVVLNILRMGSSMNGVFVSAGY GIDLELSTEICSQLLLNNTTIEPIRAADLESRRLVRENFDGNEKLE
MGEVQLVLAVTAILISFKCLLIPAYVSTDFEVHRNWMAVTWQRPLCEWYTEATSEWTLDY PPFFAYFELGLASVAHFFGFDECLVISKTPRFSRRILIFQRFSVIFCDILLLSALYTPSA LHV
|
References |
Rual JF, Ceron J, Koreth J, Hao T, Nicot AS, Hirozane-Kishikawa T, Vandenhaute J, Orkin SH, Hill DE, van den Heuvel S, Vidal M
Genome Res.
(2004)
14
(10B)
:2162-8
[PMID : 15489339]
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library.
Ceron J, Rual JF, Chandra A, Dupuy D, Vidal M, van den Heuvel S
BMC Dev. Biol.
(2007)
7
:30
[PMID : 17417969]
Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity.
|
Functional Descriptions |
C08H9.3
none available
|
Deletion Mutants |
|
In Situ |
In Situ
|
Expression |
Expression
|
WBGene00007464
Phenotype
Homology_paralog
|
|
Phenotype |
Definition |
RNAi / Allele |
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
protruding vulva
|
"Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." [WB:WBPaper00004408, WB:WBPerson2021]
|
|
reduced brood size
|
"The characteristic number of offspring produced is lower compared to that of control animals." [WB:WBPerson557]
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
sterile
|
"Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce." [GO:0000003, WB:WBPerson712]
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|