JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002861
Submitter
The Noguchi Institute
Reaction ID
R-0000-002861
Regist Date
2012/06/21 20:00:34
REACTANT
MOLECULE ID
JCGG-COM0003752 (Reaction Tree)
Skeleton
JCGG-STR028522
Mol
0.18 mmol
MOLECULE ID
JCGG-COM0000491
Reactant Type
AcOH
Mol
1.8 mmol
MOLECULE ID
JCGG-COM0001022
Reactant Type
TBAF (1 M in THF)
Mol
3.5 mmol
PRODUCT
MOLECULE ID
JCGG-COM0003753 (Reaction Tree)
Skeleton
JCGG-STR028522
Yield
96%
REACTION DETAIL
Reaction Time
20 hours
Reaction Temp
room temp
Solvent
THF (2mL)
COMMENT
Keywords: Biantennary, N-glycans, LacNAc, LacdiNAc, SPPS
REFERENCE
Reference Id
REF-0000-000371
Issn
Electronic
Doi
10.1021/jo200149d
PubMed ID
21612260
Journal Name
The Journal of organic chemistry. (2011) 76 (13): 5229-39.
Article Title
Synthesis of biantennary complex-type nonasaccharyl asn building blocks for solid-phase glycopeptide synthesis.
Author
Masashi, Hagiwara; Mizuki, Dohi; Yuko, Nakahara; Keiko, Komatsu; Yuya, Asahina; Akiharu, Ueki; Hironobu, Hojo; Yoshiaki, Nakahara; Yukishige, Ito
Affiliation
Department of Applied Biochemistry, Institute of Glycoscience, Tokai University, 4-1-1 Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan.
Reference Id
REF-0000-000372
Source
J. Org. Chem. 2011, 76, 5229-5239
Doi
10.1021/jo200149d

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)