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Glycan Syntheses |
JCGG ID |
JCGG-RAC0002779 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-002779
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Regist Date |
2012/06/21 19:47:43 | ||||
| REACTANT | |||||
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Mol |
1.15 mmol | ||||
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Reactant Type |
TEMPO | ||||
Mol |
0.23 mmol | ||||
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Reactant Type |
BAIB | ||||
Mol |
2.88 mmol | ||||
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Reactant Type |
MeI | ||||
Mol |
3.45 mmol | ||||
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Reactant Type |
K2CO3 | ||||
Mol |
3.45 mmol | ||||
| PRODUCT | |||||
MOLECULE ID |
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Yield |
71% | ||||
| REACTION DETAIL | |||||
Reaction Time |
1.5 hours, overnight | ||||
Reaction Temp |
room temp, room temp | ||||
Solvent |
CH2Cl2/H2O = 4mL/2mL, dry DMF (10mL) | ||||
Comment |
1) 15a+TEMPO, BAIB, 2) +all the rest | ||||
| The reactants were mixed at 0 degree in Celsius before stirred at room temperature. (first phase) | |||||
| COMMENT | |||||
| Keywords: mannuronic acids, mannopyranosides, mannopyranosyl methyl uronate, all-cis-linked tetrasaccharide | |||||
| There are multiple phases in this reaction. | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000367 | ||||
Issn |
Electronic | ||||
Doi |
10.1021/jo201179p | ||||
PubMed ID |
21793528 | ||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (18): 7301-15. | ||||
Article Title |
Stereoselective synthesis of 2,3-diamino-2,3-dideoxy-β-D-mannopyranosyl uronates. | ||||
Author |
Marthe T C, Walvoort; Gert-Jan, Moggré; Gerrit, Lodder; Herman S, Overkleeft; Jeroen D C, Codée; Gijsbert A, van der Marel | ||||
Affiliation |
Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands. | ||||
Reference Id |
REF-0000-000368 | ||||
Source |
J. Org. Chem. 2011, 76, 7301-7315 | ||||
Doi |
10.1021/jo201179p | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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