JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0002752
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-002752
Regist Date
 2012/06/21 19:45:27
REACTANT
MOLECULE ID
 JCGG-COM0000024 (Reaction Tree)
Skeleton
JCGG-STR032527
Mol
 2.1 mmol
MOLECULE ID
 JCGG-COM0000099
Reactant Type
 BF3*OEt2
Mol
 6.3 mmol
MOLECULE ID
 JCGG-COM0003596
Reactant Type
 1,3-propanediol
Mol
 4.6 mmol
PRODUCT
MOLECULE ID
 JCGG-COM0003597 (Reaction Tree)
Skeleton
JCGG-STR032527
Yield
 18%
REACTION DETAIL
Reaction Time
 57 hours
Reaction Temp
 room temp
Solvent
 CH2Cl2/MeCN = 1/1 (13mL)
Comment
 The reactants were mixed at 0 degree in Celsius before stirred at room temperature.
COMMENT
Keywords: trityl, photolabile, PPGs, electron-donating substituents, m-dimethylamino, photochemical deprotection
REFERENCE
Reference Id
 REF-0000-000365
Issn
 Electronic
Doi
 10.1021/jo200692c
PubMed ID
 21612261
Journal Name
 The Journal of organic chemistry. (2011) 76 (15): 5873-81.
Article Title
 Development of trityl-based photolabile hydroxyl protecting groups.
Author
 Lei, Zhou; Haishen, Yang; Pengfei, Wang
Affiliation
 Department of Chemistry, University of Alabama at Birmingham, 901 14th Street South, Birmingham, Alabama 35294, USA.
Reference Id
 REF-0000-000366
Source
 J. Org. Chem. 2011, 76, 5873-5881
Doi
 10.1021/jo200692c
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)