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Glycan Syntheses |
JCGG ID |
JCGG-RAC0002724 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-002724
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Regist Date |
2012/06/21 19:43:07 | ||||
| REACTANT | |||||
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Reactant Type |
methyl 5-(dimethylamino)-2-hydroxybenzoate | ||||
Mol |
10 mmol | ||||
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Reactant Type |
PhLi (2.0 M in dibutylether) | ||||
Mol |
40 mmol | ||||
| PRODUCT | |||||
MOLECULE ID |
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Product Type |
4-(dimethylamino)-2-(hydroxydiphenylmethyl)phenol | ||||
Yield |
80% | ||||
| REACTION DETAIL | |||||
Reaction Time |
8 hours | ||||
Reaction Temp |
room temp | ||||
Solvent |
THF (10mL) | ||||
Comment |
The reactants were mixed at -78 degree in Celsius before stirred at room temperature. | ||||
| COMMENT | |||||
| Keywords: trityl, photolabile, PPGs, electron-donating substituents, m-dimethylamino, photochemical deprotection | |||||
| The reaction is explained in text only. | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000365 | ||||
Issn |
Electronic | ||||
Doi |
10.1021/jo200692c | ||||
PubMed ID |
21612261 | ||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (15): 5873-81. | ||||
Article Title |
Development of trityl-based photolabile hydroxyl protecting groups. | ||||
Author |
Lei, Zhou; Haishen, Yang; Pengfei, Wang | ||||
Affiliation |
Department of Chemistry, University of Alabama at Birmingham, 901 14th Street South, Birmingham, Alabama 35294, USA. | ||||
Reference Id |
REF-0000-000366 | ||||
Source |
J. Org. Chem. 2011, 76, 5873-5881 | ||||
Doi |
10.1021/jo200692c | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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