JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002673
Submitter
The Noguchi Institute
Reaction ID
R-0000-002673
Regist Date
2012/06/21 19:37:01
REACTANT
MOLECULE ID
JCGG-COM0003476 (Reaction Tree)
Mol
0.10 mmol
MOLECULE ID
JCGG-COM0003481 (Reaction Tree)
Reactant Type
acyl chloride (in 1.25 mL of THF)
Mol
less than 0.11 mmol
PRODUCT
MOLECULE ID
JCGG-COM0003482 (Reaction Tree)
Yield
76%
REACTION DETAIL
Reaction Time
2 hours
Reaction Temp
NOT specified
Solvent
THF/NaOAc(aq, 8M) = 1/1
COMMENT
Keywords: building block, ceramides, glycolipids, galactosyl-phytosphingosine, KRN7000
REFERENCE
Reference Id
REF-0000-000361
Issn
Electronic
Doi
10.1021/jo102064p
PubMed ID
21155575
Journal Name
The Journal of organic chemistry. (2011) 76 (1): 320-3.
Article Title
Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids.
Author
Peter J, Jervis; Liam R, Cox; Gurdyal S, Besra
Affiliation
School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Reference Id
REF-0000-000362
Source
J. Org. Chem. 2011, 76, 320-323
Doi
10.1021/jo102064p

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)