JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002667
Submitter
The Noguchi Institute
Reaction ID
R-0000-002667
Regist Date
2012/06/21 19:36:33
REACTANT
MOLECULE ID
JCGG-COM0003474 (Reaction Tree)
Mol
0.19 mmol
MOLECULE ID
JCGG-COM0000110
Reactant Type
TFA
Mol
6.62 mmol
PRODUCT
MOLECULE ID
JCGG-COM0003475 (Reaction Tree)
Yield
quantitative
REACTION DETAIL
Reaction Time
30 minutes
Reaction Temp
room temp
Solvent
CH2Cl2 (5.0mL)
Comment
TFA was added dropwise over 5 minutes.
COMMENT
Keywords: building block, ceramides, glycolipids, galactosyl-phytosphingosine, KRN7000
REFERENCE
Reference Id
REF-0000-000361
Issn
Electronic
Doi
10.1021/jo102064p
PubMed ID
21155575
Journal Name
The Journal of organic chemistry. (2011) 76 (1): 320-3.
Article Title
Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids.
Author
Peter J, Jervis; Liam R, Cox; Gurdyal S, Besra
Affiliation
School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Reference Id
REF-0000-000362
Source
J. Org. Chem. 2011, 76, 320-323
Doi
10.1021/jo102064p

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)