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Glycan Syntheses |
JCGG ID |
JCGG-RAC0002659 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-002659
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Regist Date |
2012/06/21 19:35:47 | ||||
| REACTANT | |||||
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Reactant Type |
phytosphingosine | ||||
Mol |
31.5 mmol | ||||
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Reactant Type |
Boc2O | ||||
Mol |
33.0 mmol | ||||
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Reactant Type |
TEA | ||||
Mol |
37.8 mmol | ||||
| PRODUCT | |||||
MOLECULE ID |
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Yield |
88% | ||||
| REACTION DETAIL | |||||
Reaction Time |
18 hours | ||||
Reaction Temp |
NOT specified | ||||
Solvent |
THF (250mL) | ||||
| COMMENT | |||||
| Keywords: building block, ceramides, glycolipids, galactosyl-phytosphingosine, KRN7000 | |||||
| ATTENTION: There is a numerical discrepancy between the scheme and the written method. (the number of % yield) | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000361 | ||||
Issn |
Electronic | ||||
Doi |
10.1021/jo102064p | ||||
PubMed ID |
21155575 | ||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (1): 320-3. | ||||
Article Title |
Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids. | ||||
Author |
Peter J, Jervis; Liam R, Cox; Gurdyal S, Besra | ||||
Affiliation |
School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom. | ||||
Reference Id |
REF-0000-000362 | ||||
Source |
J. Org. Chem. 2011, 76, 320-323 | ||||
Doi |
10.1021/jo102064p | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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