JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002610
Submitter
The Noguchi Institute
Reaction ID
R-0000-002610
Regist Date
2012/06/21 19:31:03
REACTANT
MOLECULE ID
JCGG-COM0003389 (Reaction Tree)
Mol
0.66 mmol
MOLECULE ID
JCGG-COM0000415
Reactant Type
Pd(OH)2/C
Weight
500 mg
MOLECULE ID
JCGG-COM0000414
Reactant Type
H2 (gas)
PRODUCT
MOLECULE ID
JCGG-COM0003390 (Reaction Tree)
Yield
98%
REACTION DETAIL
Reaction Time
46 hours
Reaction Temp
room temp
Solvent
EtOH (50mL)
COMMENT
Keywords: carbamyl glucuronidation, metabolism, secondary amine drugs, glucuronyl p-nitrophenyl carbonates
REFERENCE
Reference Id
REF-0000-000357
Issn
Electronic
Doi
10.1021/jo200238d
PubMed ID
21598979
Journal Name
The Journal of organic chemistry. (2011) 76 (13): 5429-32.
Article Title
Reagents for stereoselective preparation of N-carbamyl β-D-glucuronides.
Author
William H, Bunnelle
Affiliation
Abbott Laboratories, Neuroscience Research, Building AP9A, Department R4MN, 100 Abbott Park Road, Abbott Park, Illinois 60064-6117, United States. william.h.bunnelle@abbott.com
Reference Id
REF-0000-000358
Source
J. Org. Chem. 2011, 76, 5429-5432
Doi
10.1021/jo200238d

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)