JCGG ID |
JCGG-RAC0002606 | |||||||
Submitter |
The Noguchi Institute | |||||||
Reaction ID |
R-0000-002606 | |||||||
Regist Date |
2012/06/21 19:30:45 | |||||||
REACTANT | ||||||||
|
|
|
||||||
Mol |
0.199 mmol | |||||||
|
|
|||||||
Mol |
0.200 mmol | |||||||
|
|
|||||||
Reactant Type |
TEA | |||||||
Mol |
0.7 mmol | |||||||
PRODUCT | ||||||||
MOLECULE ID |
|
|
||||||
Yield |
88% | |||||||
REACTION DETAIL | ||||||||
Reaction Time |
75 minutes | |||||||
Reaction Temp |
room temp | |||||||
Solvent |
CH2Cl2 (5mL) | |||||||
COMMENT | ||||||||
Keywords: carbamyl glucuronidation, metabolism, secondary amine drugs, glucuronyl p-nitrophenyl carbonates | ||||||||
REFERENCE | ||||||||
Reference Id |
REF-0000-000357 | |||||||
Issn |
Electronic | |||||||
Doi |
10.1021/jo200238d | |||||||
PubMed ID |
21598979 | |||||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (13): 5429-32. | |||||||
Article Title |
Reagents for stereoselective preparation of N-carbamyl β-D-glucuronides. | |||||||
Author |
William H, Bunnelle | |||||||
Affiliation |
Abbott Laboratories, Neuroscience Research, Building AP9A, Department R4MN, 100 Abbott Park Road, Abbott Park, Illinois 60064-6117, United States. william.h.bunnelle@abbott.com | |||||||
Reference Id |
REF-0000-000358 | |||||||
Source |
J. Org. Chem. 2011, 76, 5429-5432 | |||||||
Doi |
10.1021/jo200238d |
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST) |