|
Glycan Syntheses |
JCGG ID |
JCGG-RAC0002605 | |||||||
Submitter |
The Noguchi Institute | |||||||
Reaction ID |
R-0000-002605
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Regist Date |
2012/06/21 19:30:38 | |||||||
| REACTANT | ||||||||
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Mol |
0.658 mmol | |||||||
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Reactant Type |
(p-NO2C6H4O)2CO | |||||||
Mol |
0.691 mmol | |||||||
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|||||||
Reactant Type |
TEA | |||||||
Mol |
1.32 mmol | |||||||
| PRODUCT | ||||||||
MOLECULE ID |
|
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Yield |
72% | |||||||
| REACTION DETAIL | ||||||||
Reaction Time |
2.5 hours | |||||||
Reaction Temp |
0 degree C | |||||||
Solvent |
CH2Cl2 (20mL) | |||||||
| COMMENT | ||||||||
| Keywords: carbamyl glucuronidation, metabolism, secondary amine drugs, glucuronyl p-nitrophenyl carbonates | ||||||||
| REFERENCE | ||||||||
Reference Id |
REF-0000-000357 | |||||||
Issn |
Electronic | |||||||
Doi |
10.1021/jo200238d | |||||||
PubMed ID |
21598979 | |||||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (13): 5429-32. | |||||||
Article Title |
Reagents for stereoselective preparation of N-carbamyl β-D-glucuronides. | |||||||
Author |
William H, Bunnelle | |||||||
Affiliation |
Abbott Laboratories, Neuroscience Research, Building AP9A, Department R4MN, 100 Abbott Park Road, Abbott Park, Illinois 60064-6117, United States. william.h.bunnelle@abbott.com | |||||||
Reference Id |
REF-0000-000358 | |||||||
Source |
J. Org. Chem. 2011, 76, 5429-5432 | |||||||
Doi |
10.1021/jo200238d | |||||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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