JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0002589
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-002589
Regist Date
 2012/06/21 19:29:09
REACTANT
MOLECULE ID
 JCGG-COM0003362 (Reaction Tree)
Reactant Type
 visnagin
MOLECULE ID
 JCGG-COM0000334
Reactant Type
 H2SO4 (25%)
MOLECULE ID
 JCGG-COM0003363
Reactant Type
 K2Cr2O7 (0.5 M)
MOLECULE ID
 JCGG-COM0000418
Reactant Type
 NaOH (1 M)
MOLECULE ID
 JCGG-COM0000421
Reactant Type
 H2O2 (30%)
PRODUCT
MOLECULE ID
 JCGG-COM0003364 (Reaction Tree)
Yield
 NOT specified
REACTION DETAIL
Reaction Time
 NOT specified
Reaction Temp
 NOT specified
Solvent
 NOT specified
Comment
 1) visnagin+H2SO4, K2Cr2O7, 2) +NaOH, H2O2
Very few were described regarding this reaction.
COMMENT
Keywords: 2-methylchromone-7-O-rutinosides, cytotoxicity, human tumor cell lines, acidic labile, 2-methylchromone aglycon
The details regarding this reaction are described in another paper in References.
REFERENCE
Reference Id
 REF-0000-000355
Issn
 Electronic
Doi
 10.1021/jo102325s
PubMed ID
 21366286
Journal Name
 The Journal of organic chemistry. (2011) 76 (7): 2265-8.
Article Title
 Concise synthesis of 5-methoxy-6-hydroxy-2-methylchromone-7-O- and 5-hydroxy-2-methylchromone-7-O-rutinosides. Investigation of their cytotoxic activities against several human tumor cell lines.
Author
 Baolin, Wu; Wenpeng, Zhang; Zhonghua, Li; Li, Gu; Xin, Wang; Peng George, Wang
Affiliation
 Department of Chemistry, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, USA.
Reference Id
 REF-0000-000356
Source
 J. Org. Chem. 2011, 76, 2265-2268
Doi
 10.1021/jo102325s
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)