JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002452
Submitter
The Noguchi Institute
Reaction ID
R-0000-002452
Regist Date
2012/06/21 19:15:32
REACTANT
MOLECULE ID
JCGG-COM0003186 (Reaction Tree)
MOLECULE ID
JCGG-COM0000375
Reactant Type
PhCH(OMe)2
MOLECULE ID
JCGG-COM0000498
Reactant Type
p-TSA
PRODUCT
MOLECULE ID
JCGG-COM0003187 (Reaction Tree)
Skeleton
JCGG-STR008690
Product Type
alpha
Yield
NOT specified
MOLECULE ID
JCGG-COM0003188 (Reaction Tree)
Skeleton
JCGG-STR008276
Product Type
beta
Yield
NOT specified
REACTION DETAIL
Reaction Time
NOT specified
Reaction Temp
room temp
Solvent
DMF
Comment
Very few were described regarding this reaction.
COMMENT
Keywords: triazole, heparosan, chondroitin, copper catalyzed azide-alkyne cycloaddition, CuAAC, azido-glucuronic acid, glucosamine, galactosamine
REFERENCE
Reference Id
REF-0000-000343
Issn
Electronic
Doi
10.1021/jo200076z
PubMed ID
21438620
Journal Name
The Journal of organic chemistry. (2011) 76 (9): 3181-93.
Article Title
Design and synthesis of unnatural heparosan and chondroitin building blocks.
Author
Smritilekha, Bera; Robert J, Linhardt
Affiliation
Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
Reference Id
REF-0000-000344
Source
J. Org. Chem. 2011, 76, 3181-3193
Doi
10.1021/jo200076z

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)