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Glycan Syntheses |
JCGG ID |
JCGG-RAC0002427 | |||||||
Submitter |
The Noguchi Institute | |||||||
Reaction ID |
R-0000-002427
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Regist Date |
2012/06/21 19:13:25 | |||||||
| REACTANT | ||||||||
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Mol |
1.0 equiv. | |||||||
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Reactant Type |
benzyl 2,2,2-trichloroacetimidate | |||||||
Mol |
4.0 equiv. | |||||||
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Reactant Type |
TfOH | |||||||
Mol |
0.05 equiv. | |||||||
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Reactant Type |
KOH | |||||||
Mol |
NOT specified | |||||||
| PRODUCT | ||||||||
MOLECULE ID |
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Yield |
77% | |||||||
| REACTION DETAIL | ||||||||
Reaction Time |
4 hours, 3 hours | |||||||
Reaction Temp |
room temp, reflux | |||||||
Solvent |
cyclohexane/CH2Cl2 = 4/1, MeOH | |||||||
Comment |
1) +all except KOH, 2) +KOH | |||||||
| COMMENT | ||||||||
| Keywords: acylation, pivaloylation, pivaloyl chloride, esterifying, regioisomers | ||||||||
| There are multiple phases in this reaction. | ||||||||
| REFERENCE | ||||||||
Reference Id |
REF-0000-000341 | |||||||
Issn |
Electronic | |||||||
PubMed ID |
11672212 | |||||||
Journal Name |
The Journal of organic chemistry. (1998) 63 (17): 6035-6038. | |||||||
Article Title |
Regioselective Acylation of Hexopyranosides with Pivaloyl Chloride. | |||||||
Author |
Lu, Jiang; Tak-Hang, Chan | |||||||
Affiliation |
Department of Chemistry, McGill University, Montréal, Québec H3A 2K6, Canada. | |||||||
Reference Id |
REF-0000-000342 | |||||||
Source |
J. Org. Chem. 1998, 63, 6035-6038 | |||||||
Doi |
10.1021/jo980294v | |||||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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