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Glycan Syntheses |
JCGG ID |
JCGG-RAC0002205 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-002205
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Regist Date |
2012/06/21 18:49:35 | ||||
| REACTANT | |||||
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Mol |
0.11 mmol | ||||
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Mol |
0.10 mmol | ||||
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Reactant Type |
BnBr | ||||
Mol |
0.33 to 0.99 mol | ||||
| PRODUCT | |||||
MOLECULE ID |
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Product Type |
alpha | ||||
Yield |
70%(alpha/beta=more than 25/1) | ||||
MOLECULE ID |
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Product Type |
beta | ||||
Yield |
70%(alpha/beta=more than 25/1) | ||||
| REACTION DETAIL | |||||
Reaction Time |
24 to 36 hours | ||||
Reaction Temp |
55 degree C | ||||
Solvent |
(ClCH2)2 | ||||
Comment |
The donor, the acceptor, and molecular sieves (3 A) were mixed and stirred for 1 hour before the reaction. | ||||
| MS 3A was included in the solvent. | |||||
| COMMENT | |||||
| Keywords: S-thiazolinyl, STaz, S-benzoxazolyl, SBox, S-ethyl, anomeric leaving groups, activation, monosaccharide building blocks | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000325 | ||||
Issn |
Electronic | ||||
Doi |
10.1021/jo201117s | ||||
PubMed ID |
21797272 | ||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (18): 7388-98. | ||||
Article Title |
On orthogonal and selective activation of glycosyl thioimidates and thioglycosides: application to oligosaccharide assembly. | ||||
Author |
Sophon, Kaeothip; Alexei V, Demchenko | ||||
Affiliation |
Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA. | ||||
Reference Id |
REF-0000-000326 | ||||
Source |
J. Org. Chem. 2011, 76, 7388-7398 | ||||
Doi |
10.1021/jo201117s | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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