JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002157
Submitter
The Noguchi Institute
Reaction ID
R-0000-002157
Regist Date
2012/06/21 18:43:26
REACTANT
MOLECULE ID
JCGG-COM0002801 (Reaction Tree)
Reactant Type
intermediate
Mol
0.0087 to 0.01 mmol
MOLECULE ID
JCGG-COM0000489
Reactant Type
NH2NH2*H2O
Volume
0.24 mL
PRODUCT
MOLECULE ID
JCGG-COM0002802 (Reaction Tree)
Yield
87%(at least)
REACTION DETAIL
Reaction Time
8 hours
Reaction Temp
room temp
Solvent
MeOH
COMMENT
Keywords: mannose-6-phosphate, M6P, N-linked glycans, eukaryotic cells, N-acetylglucosamine, GlcNAc, sequential deprotection
REFERENCE
Reference Id
REF-0000-000321
Issn
Electronic
Doi
10.1021/jo2010999
PubMed ID
21955083
Journal Name
The Journal of organic chemistry. (2011) 76 (21): 8682-9.
Article Title
Chemical synthesis of N-linked glycans carrying both mannose-6-phosphate and GlcNAc-mannose-6-phosphate motifs.
Author
Yunpeng, Liu; Gong, Chen
Affiliation
Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Reference Id
REF-0000-000322
Source
J. Org. Chem., 2011, 76 (21), pp 8682-8689
Doi
10.1021/jo2010999

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