JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0002122
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-002122
Regist Date
 2012/06/21 18:36:24
REACTANT
MOLECULE ID
 JCGG-COM0002769 (Reaction Tree)
Skeleton
JCGG-STR015611
Reactant Type
 (in 1 mL of CH2Cl2)
Mol
 0.14 mmol
MOLECULE ID
 JCGG-COM0002770
Reactant Type
 oleic acid
Mol
 0.14 mmol
MOLECULE ID
 JCGG-COM0000652
Reactant Type
 DCC
Mol
 0.28 mmol
MOLECULE ID
 JCGG-COM0000500
Reactant Type
 DMAP
Mol
 0.07 mmol
PRODUCT
MOLECULE ID
 JCGG-COM0002771 (Reaction Tree)
Skeleton
JCGG-STR015611
Yield
 60%
MOLECULE ID
 JCGG-COM0002772 (Reaction Tree)
Skeleton
JCGG-STR015611
Yield
 17%
REACTION DETAIL
Reaction Time
 more than 5 hours
Reaction Temp
 room temp
Solvent
 CH2Cl2
Comment
 The reactants were mixed at 0 degree in Celsius, and allowed to warm to room temperature.
The addition of 4 was performed after the addition of all the other reactants.
4 was added in a slow, dropwise manner.
COMMENT
Keywords: maradolipid, C. elegans, trehalose
REFERENCE
Reference Id
 REF-0000-000319
Issn
 Electronic
Doi
 10.1021/jo200979n
PubMed ID
 21739985
Journal Name
 The Journal of organic chemistry. (2011) 76 (16): 6866-70.
Article Title
 Synthesis of maradolipid.
Author
 Vikram A, Sarpe; Suvarn S, Kulkarni
Affiliation
 Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India.
Reference Id
 REF-0000-000320
Source
 J. Org. Chem. 2011, 76, 6866-6870
Doi
 10.1021/jo200979n
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)