JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0002112
Submitter
The Noguchi Institute
Reaction ID
R-0000-002112
Regist Date
2012/06/21 18:35:43
REACTANT
MOLECULE ID
JCGG-COM0002732 (Reaction Tree)
Reactant Type
alpha
Mol
0.46 mmol
MOLECULE ID
JCGG-COM0002733
Reactant Type
HCC-CO2Et
Mol
0.46 mmol
MOLECULE ID
JCGG-COM0000704
Reactant Type
base
Mol
0.46 mmol
PRODUCT
MOLECULE ID
JCGG-COM0002734 (Reaction Tree)
Product Type
E
Yield
87%(E/Z=73/27)
MOLECULE ID
JCGG-COM0002735 (Reaction Tree)
Product Type
Z
Yield
87%(E/Z=73/27)
REACTION DETAIL
Reaction Time
12 hours
Reaction Temp
0 degree C
Solvent
Et2O
COMMENT
Keywords: glycosylthiols, bis-trimethyl-silyl sulfide, sterically hindered S-nucleophile
REFERENCE
Reference Id
REF-0000-000317
Issn
Electronic
Doi
10.1021/jo200624e
PubMed ID
21800823
Journal Name
The Journal of organic chemistry. (2011) 76 (18): 7539-45.
Article Title
Synthesis of glycosylthiols and reactivity studies.
Author
Ravindra T, Dere; Amit, Kumar; Vipin, Kumar; Xiangming, Zhu; Richard R, Schmidt
Affiliation
Fachbereich Chemie, Universita?t Konstanz, Fach 725, D-78457 Konstanz, Germany.
Reference Id
REF-0000-000318
Source
J. Org. Chem. 2011, 76, 7539-7545
Doi
10.1021/jo200624e

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)