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Glycan Syntheses |
JCGG ID |
JCGG-RAC0002045 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-002045
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Regist Date |
2012/06/21 18:27:53 | ||||
| REACTANT | |||||
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Reactant Type |
intermediate 1 | ||||
Mol |
1.184 to 1.6 mmol | ||||
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Reactant Type |
(MeO)2P(O)H | ||||
Mol |
16.3 mmol | ||||
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Reactant Type |
DMAN | ||||
Mol |
4.0 mmol | ||||
| PRODUCT | |||||
MOLECULE ID |
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Product Type |
intermediate 2 | ||||
Yield |
74%(at least) | ||||
| REACTION DETAIL | |||||
Reaction Time |
1 day | ||||
Reaction Temp |
room temp | ||||
Solvent |
dry MeCN | ||||
Comment |
Before the reaction, (MeO)2P(O)H and DMAN in dry MeCN were dried over MS 3A. | ||||
| COMMENT | |||||
| Keywords: alpha-D-glycosyl boranophosphate, phosphoramidite, condensation, boronation, terminal deprotection, Leishmania glycocalyx lipophosphoglycans | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000315 | ||||
Issn |
Electronic | ||||
Doi |
10.1021/jo102584g | ||||
PubMed ID |
21381786 | ||||
Journal Name |
The Journal of organic chemistry. (2011) 76 (8): 2648-59. | ||||
Article Title |
Synthesis of oligo(α-D-glycosyl phosphate) derivatives by a phosphoramidite method via boranophosphate intermediates. | ||||
Author |
Shoichi, Fujita; Natsuhisa, Oka; Fumiko, Matsumura; Takeshi, Wada | ||||
Affiliation |
Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Bioscience Building 702, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan. | ||||
Reference Id |
REF-0000-000316 | ||||
Source |
J. Org. Chem. 2011, 76, 2648-2659 | ||||
Doi |
10.1021/jo102584g | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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