|
Glycan Syntheses |
JCGG ID |
JCGG-RAC0001868 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-001868
|
||||
Regist Date |
2012/06/21 18:10:23 | ||||
| REACTANT | |||||
|
|
|
||||
Reactant Type |
onate | ||||
Mol |
5.4 mmol | ||||
|
|
|
||||
Reactant Type |
TIPDSCl2 (in DMF with imidazole) | ||||
Mol |
5.4 + 1.6 mmol | ||||
|
|
|
||||
Reactant Type |
imidazole (in DMF with TIPDSCl2) | ||||
Mol |
13 + 3.9 mmol | ||||
| PRODUCT | |||||
MOLECULE ID |
|
|
|||
Yield |
80% | ||||
| REACTION DETAIL | |||||
Reaction Time |
4 hours, 5 hours | ||||
Reaction Temp |
-10 degree C, 0 degree C | ||||
Solvent |
dry DMF, dry DMF | ||||
Comment |
1) onate+TIPDSCl2, imidazole, 2) second addition of TIPDSCl2 and imidazole | ||||
| The solutions of TIPDSCl2 and imidazole in dry DMF were prepared independently before the reaction. | |||||
| COMMENT | |||||
| Keywords: synthesis, silyl acetals, TIPSCl2 | |||||
| There are multiple steps in this reaction. | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000253 | ||||
Source |
Essentials of Carbohydrate Chemistry and Biochemistry | ||||
Reference Id |
REF-0000-000254 | ||||
Source |
ISBN 978-3-527-31528-4 | ||||
Reference Id |
REF-0000-000280 | ||||
Source |
Carbohydr. Res. 190, 191 (1989) | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
|