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Glycan Syntheses |
JCGG ID |
JCGG-RAC0001827 | |||||||
Submitter |
The Noguchi Institute | |||||||
Reaction ID |
R-0000-001827
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Regist Date |
2012/06/21 18:06:47 | |||||||
| REACTANT | ||||||||
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Reactant Type |
D-mannose | |||||||
Mol |
138.9 mmol | |||||||
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Reactant Type |
acetyl chloride | |||||||
Mol |
0.35 mol | |||||||
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Reactant Type |
allyl alcohol (solvent) | |||||||
Volume |
300 mL | |||||||
| PRODUCT | ||||||||
MOLECULE ID |
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Yield |
48% | |||||||
| REACTION DETAIL | ||||||||
Reaction Time |
4 hours | |||||||
Reaction Temp |
70 degree C | |||||||
Solvent |
allyl alcohol | |||||||
Comment |
The reactants were mixed at 0 degree in Celsius before stirred at below 70 degree. | |||||||
| COMMENT | ||||||||
| Keywords: synthesis, Fischer glycosylation, allyl glycosides, isomerization, 2,3,4,6-tetra-O-benzyl-alpha-D-mannopyranose | ||||||||
| The reaction is the 1st part of the sequence. | ||||||||
| REFERENCE | ||||||||
Reference Id |
REF-0000-000253 | |||||||
Source |
Essentials of Carbohydrate Chemistry and Biochemistry | |||||||
Reference Id |
REF-0000-000254 | |||||||
Source |
ISBN 978-3-527-31528-4 | |||||||
Reference Id |
REF-0000-000258 | |||||||
Source |
J. Carbohydr. Chem. 16, 877 (1997) | |||||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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