JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0001817
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-001817
Regist Date
 2012/06/21 18:03:10
REACTANT
MOLECULE ID
 JCGG-COM0002370 (Reaction Tree)
Skeleton
JCGG-STR027869
Mol
 0.43 mmol
MOLECULE ID
 JCGG-COM0000629 (Reaction Tree)
Mol
 0.72 mmol
MOLECULE ID
 JCGG-COM0000129
Reactant Type
 NIS
Mol
 2.5 mmol
MOLECULE ID
 JCGG-COM0000111
Reactant Type
 TfOH
Mol
 0.73 mmol
PRODUCT
MOLECULE ID
 JCGG-COM0002371 (Reaction Tree)
Skeleton
JCGG-STR028672
Product Type
 alpha
Yield
 58%
REACTION DETAIL
Reaction Time
 overnight
Reaction Temp
 -35 degree C
Solvent
 dry MeCN
Comment
 46, 12, and MS 3A were mixed and stirred for 5 hours at room temperature before the reaction.
MS 3A was included in the solvent.
COMMENT
Keywords: synthesis, sialyl glycosides, sialylation, Lewis X, trisaccharide
REFERENCE
Reference Id
 REF-0000-000196
Source
 PREPARATIVE CARBOHYDRATE CHEMISTRY
Reference Id
 REF-0000-000197
Source
 ISBN 0-8247-9802-3
Reference Id
 REF-0000-000247
Source
 J. Carbohydr. Chem. 12:1203 (1993)
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)