Reaction:JCGG-RAC0001814

JCGG ID

JCGG-RAC0001814

Submitter

The Noguchi Institute

Reaction ID

R-0000-001814

Regist Date

2012/06/21 18:02:49

REACTANT

MOLECULE ID

JCGG-COM0000629 (Reaction Tree)

Mol

18.3 mmol

MOLECULE ID

JCGG-COM0002320 (Reaction Tree)

Skeleton

JCGG-STR031555

Mol

10 mmol

MOLECULE ID

JCGG-COM0000129

Reactant Type

NIS

Mol

36.8 mmol

MOLECULE ID

JCGG-COM0000111

Reactant Type

TfOH

Mol

3.6 mmol

PRODUCT

MOLECULE ID

JCGG-COM0002322 (Reaction Tree)

Skeleton

JCGG-STR024648

Product Type

alpha

Yield

70%

REACTION DETAIL

Reaction Time

2.5 hours

Reaction Temp

-35 degree C

Solvent

dry MeCN/CH2Cl2 = 50mL/5mL

Comment

12, 14, and MS 3A were mixed and stirred overnight at room temperature before the reaction.

MS 3A was included in the solvent.

COMMENT

Keywords: synthesis, sialyl glycosides, sialylation, 6-O-benzoyl-galactose

REFERENCE

Reference Id

REF-0000-000196

Source

PREPARATIVE CARBOHYDRATE CHEMISTRY

Reference Id

REF-0000-000197

Source

ISBN 0-8247-9802-3

Reference Id

REF-0000-000244

Source

J. Carbohydr. Chem. 10:493 (1991)

Reference Id

REF-0000-000245

Source

ACS Symp. Ser. 560 (P. Kovac, ed.), ACS, Washington DC, 1994, p.184