Reaction:JCGG-RAC0001716

JCGG ID

JCGG-RAC0001716

Submitter

The Noguchi Institute

Reaction ID

R-0000-001716

Regist Date

2012/06/21 17:42:56

REACTANT

MOLECULE ID

JCGG-COM0001950 (Reaction Tree)

Mol

1 mmol

MOLECULE ID

JCGG-COM0000071 (Reaction Tree)

Skeleton

JCGG-STR032525

Mol

1.2 mmol

MOLECULE ID

JCGG-COM0000099

Reactant Type

BF3*OEt2 (0.1 M in Et2O/CH2Cl2=1/1)

Volume

1 mL

PRODUCT

MOLECULE ID

JCGG-COM0001951 (Reaction Tree)

Yield

90%

REACTION DETAIL

Reaction Time

(5 to 10) + 15 minutes

Reaction Temp

0 degree C

Solvent

dry CH2Cl2

Comment

38, 39, and MS 4A were mixed and stirred for 30 minutes at room temperature before the reaction.

MS 4A was included in the solvent.

BF3*OEt2 was added dropwise within 5 to 10 minutes.

COMMENT

Keywords: glycosylation, O-glycosyl trichloroacetimidates

The reaction is the 1st part of the sequence.

REFERENCE

Reference Id

REF-0000-000196

Source

PREPARATIVE CARBOHYDRATE CHEMISTRY

Reference Id

REF-0000-000197

Source

ISBN 0-8247-9802-3

Reference Id

REF-0000-000216

Source

Synthesis p. 694 (1988)