Reaction:JCGG-RAC0001660

JCGG ID		JCGG-RAC0001660
Submitter		The Noguchi Institute
Reaction ID		R-0000-001660
Regist Date		2012/06/21 17:33:27
REACTANT
MOLECULE ID		JCGG-COM0002120 (Reaction Tree)
	Reactant Type	bromide
	Mol	0.5 mmol
MOLECULE ID		JCGG-COM0002121
	Reactant Type	alcohol
	Volume	0.5 mL
MOLECULE ID		JCGG-COM0000032
	Reactant Type	AgClO4
	Weight	15 mg
MOLECULE ID		JCGG-COM0001699
	Reactant Type	Ag2CO3
	Weight	150 mg
PRODUCT
MOLECULE ID		JCGG-COM0002122 (Reaction Tree)
	Yield	81%
REACTION DETAIL
Reaction Time		1 hour, 20 minutes, 1 + 6 hours
Reaction Temp		20 degree C, 20 degree C, 20 degree C
Solvent		PhCH3/CH2Cl2 = 1/1, PhCH3/CH2Cl2 = 1/1, PhCH3/CH2Cl2 = 1/1
Comment		1) alcohol+MS 4A, Ag2CO3, 2) +AgClO4, 3) +bromide
		MS 4A was included in the solvent.
		The reaction was conducted with exclusion of light. (first step)
		The bromide was added dropwise over 1 hour. (third step)
COMMENT
Keywords: synthesis of glycopeptide, O-glycan
There are multiple steps in this reaction.
REFERENCE
Reference Id		REF-0000-000073
	Source	第4版実験化学講座 (26), 丸善
Reference Id		REF-0000-000074
	Source	ISBN 4-621-03702-1
Reference Id		REF-0000-000194
	Source	H. Paulsen and M. Paal, Carbohydr. Res., 135, 53 (1984) ; H. Paulsen and M. Paal, ibid., 135, 71 (1984)