JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0001612
Submitter
The Noguchi Institute
Reaction ID
R-0000-001612
Regist Date
2012/06/21 17:26:01
REACTANT
MOLECULE ID
JCGG-COM0002058 (Reaction Tree)
MOLECULE ID
JCGG-COM0000110
Reactant Type
TFA (50% in CH2Cl2)
MOLECULE ID
JCGG-COM0000530
Reactant Type
NaOMe (in MeOH)
MOLECULE ID
JCGG-COM0000086
Reactant Type
Ac2O
PRODUCT
MOLECULE ID
JCGG-COM0002059 (Reaction Tree)
Yield
24%(at least)
REACTION DETAIL
Reaction Time
NOT specified, NOT specified, NOT specified
Reaction Temp
NOT specified, NOT specified, NOT specified
Solvent
CH2Cl2, MeOH, pyridine
Comment
1) 8+TFA, 2) +NaOMe, 3) +Ac2O
Very few were described regarding this reaction.
COMMENT
Keywords: biological activity, carbohydrates, conformation analysis, lectins, synthesis design
There are multiple phases in this reaction.
REFERENCE
Reference Id
REF-0000-000189
Issn
Print
Doi
10.1002/chem.200400831
PubMed ID
15770712
Journal Name
Chemistry (Weinheim an der Bergstrasse, Germany). (2005) 11 (10): 3032-8.
Article Title
Synthesis and evaluation of 5-thio-L-fucose-containing oligosaccharide.
Author
Masayuki, Izumi; Osamu, Tsuruta; Yasuhiro, Kajihara; Shin, Yazawa; Hideya, Yuasa; Hironobu, Hashimoto
Affiliation
Department of Life Science, Graduate school of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Yokohama 226-8501, Japan.masayuki.izumi@aist.go.jp
Reference Id
REF-0000-000190
Source
Chem. Eur. J. 2005, 11, 3032-3038
Doi
10.1002/chem.200400831

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)