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Glycan Syntheses |
JCGG ID |
JCGG-RAC0001609 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-001609
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Regist Date |
2012/06/21 17:25:39 | ||||
| REACTANT | |||||
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Mol |
0.490 mmol | ||||
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Reactant Type |
BzCN (in DMF) | ||||
Mol |
0.13 mmol | ||||
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Reactant Type |
Et3N (in DMF) | ||||
Volume |
0.21 mL | ||||
| PRODUCT | |||||
MOLECULE ID |
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Yield |
71% | ||||
| REACTION DETAIL | |||||
Reaction Time |
1 hour | ||||
Reaction Temp |
-40 degree C | ||||
Solvent |
DMF | ||||
Comment |
The reaction condition (BzCN and Et3N) selectively acylates the primary alcohol. (C-6 hydroxy group) | ||||
| NOTICE: The amount of the disaccharide exceeds that of BzCN. | |||||
| COMMENT | |||||
| Keywords: biological activity, carbohydrates, conformation analysis, lectins, synthesis design | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000189 | ||||
Issn |
|||||
Doi |
10.1002/chem.200400831 | ||||
PubMed ID |
15770712 | ||||
Journal Name |
Chemistry (Weinheim an der Bergstrasse, Germany). (2005) 11 (10): 3032-8. | ||||
Article Title |
Synthesis and evaluation of 5-thio-L-fucose-containing oligosaccharide. | ||||
Author |
Masayuki, Izumi; Osamu, Tsuruta; Yasuhiro, Kajihara; Shin, Yazawa; Hideya, Yuasa; Hironobu, Hashimoto | ||||
Affiliation |
Department of Life Science, Graduate school of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Yokohama 226-8501, Japan.masayuki.izumi@aist.go.jp | ||||
Reference Id |
REF-0000-000190 | ||||
Source |
Chem. Eur. J. 2005, 11, 3032-3038 | ||||
Doi |
10.1002/chem.200400831 | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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