Reaction:JCGG-RAC0001555

JCGG ID

JCGG-RAC0001555

Submitter

The Noguchi Institute

Reaction ID

R-0000-001555

Regist Date

2012/06/21 17:20:39

REACTANT

MOLECULE ID

JCGG-COM0001997 (Reaction Tree)

Skeleton

JCGG-STR026084

Reactant Type

disaccharide

MOLECULE ID

JCGG-COM0000498

Reactant Type

p-TsOH

MOLECULE ID

JCGG-COM0000161

Reactant Type

BnBr

MOLECULE ID

JCGG-COM0001998

Reactant Type

BaO

MOLECULE ID

JCGG-COM0001999

Reactant Type

Ba(OH)2

PRODUCT

MOLECULE ID

JCGG-COM0002000 (Reaction Tree)

Skeleton

JCGG-STR026084

Yield

72%

REACTION DETAIL

Reaction Time

3 hours, 36 hours

Reaction Temp

room temp, room temp

Solvent

acetone, DMF

Comment

1) disaccharide+p-TsOH, 2) +BnBr, BaO, Ba(OH)2

Very few were described regarding this reaction.

COMMENT

Keywords: protection of sugar hydroxy groups, cycloacetal group protection

There are multiple steps in this reaction.

REFERENCE

Reference Id

REF-0000-000073

Source

第4版実験化学講座 (26), 丸善

Reference Id

REF-0000-000074

Source

ISBN 4-621-03702-1

Reference Id

REF-0000-000183

Source

J.-C. Jacquinet, D. Duchet, M.-L. Milat, and P. Sinay, J. Chem. Soc., Perkin Trans. 1, 1981, 326