Reaction:JCGG-RAC0001487

JCGG ID

JCGG-RAC0001487

Submitter

The Noguchi Institute

Reaction ID

R-0000-001487

Regist Date

2012/06/21 17:10:48

REACTANT

MOLECULE ID

JCGG-COM0001660 (Reaction Tree)

Reactant Type

chloride (in 0.4 + 0.3 mL of CH2Cl2)

Mol

0.75 mmol (total)

MOLECULE ID

JCGG-COM0001462 (Reaction Tree)

Skeleton

JCGG-STR032527

Reactant Type

alcohol

Mol

0.5 mmol

MOLECULE ID

JCGG-COM0000624

Reactant Type

AgOSO2CF3

Mol

0.80 mmol

MOLECULE ID

JCGG-COM0001730

Reactant Type

(Me2N)2CO

Mol

1.6 mmol

PRODUCT

MOLECULE ID

JCGG-COM0001835 (Reaction Tree)

Skeleton

JCGG-STR033114

Yield

82%

REACTION DETAIL

Reaction Time

2 hours + overnight

Reaction Temp

room temp

Solvent

CH2Cl2

Comment

The chloride was added twice. (0 hour, 2 hours)

The reactants were mixed at -5 degree in Celsius before stirred at room temperature.

COMMENT

Keywords: The synthesis of 1,2-trans-glycoside, alpha-mannopyranoside

REFERENCE

Reference Id

REF-0000-000073

Source

第4版実験化学講座 (26), 丸善

Reference Id

REF-0000-000074

Source

ISBN 4-621-03702-1

Reference Id

REF-0000-000079

Source

T. Ogawa, K. Katano, K. Sasajima, and M. Matsui, Tetrahedron, 37, 2779 (1981)