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Glycan Syntheses |
JCGG ID |
JCGG-RAC0001411 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-001411
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Regist Date |
2012/06/21 16:59:21 | ||||
| REACTANT | |||||
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Mol |
2.41 micro mol | ||||
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Reactant Type |
LiOH | ||||
Mol |
131 equiv. | ||||
| PRODUCT | |||||
MOLECULE ID |
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Yield |
23% | ||||
| REACTION DETAIL | |||||
Reaction Time |
NOT specified | ||||
Reaction Temp |
room temp | ||||
Solvent |
D2O | ||||
Comment |
saponification (monitored by a NMR spectrometer) | ||||
| Before the addition of LiOH, the concentration of the solute in D2O was adjusted to 0.5 M. | |||||
| COMMENT | |||||
| Keywords: Bisubstrate-type sialyltransferase inhibitors, CMP-NeuAc, N-acetyllactosamine, lactose, sialic acid, ST6N, ST3N | |||||
| ATTENTION: There is a typo in the written method. (compound 15c should be 18c) | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000071 | ||||
Issn |
|||||
Doi |
10.1021/jo030042g | ||||
PubMed ID |
12839452 | ||||
Journal Name |
The Journal of organic chemistry. (2003) 68 (14): 5602-13. | ||||
Article Title |
Systematic syntheses and inhibitory activities of bisubstrate-type inhibitors of sialyltransferases. | ||||
Author |
Hiroshi, Hinou; Xue-Long, Sun; Yukishige, Ito | ||||
Affiliation |
RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan. | ||||
Reference Id |
REF-0000-000072 | ||||
Source |
J. Org. Chem. 2003, 68, 5602-5613 | ||||
Doi |
10.1021/jo030042g | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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