JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0001385
Submitter
The Noguchi Institute
Reaction ID
R-0000-001385
Regist Date
2012/06/21 16:56:44
REACTANT
MOLECULE ID
JCGG-COM0001595 (Reaction Tree)
Mol
0.297 mmol
MOLECULE ID
JCGG-COM0001540
Reactant Type
hydrazine acetate
Mol
1.20 equiv.
PRODUCT
MOLECULE ID
JCGG-COM0001607 (Reaction Tree)
Yield
94%
REACTION DETAIL
Reaction Time
1 hour
Reaction Temp
ambient temperature
Solvent
DMF
COMMENT
Keywords: Bisubstrate-type sialyltransferase inhibitors, CMP-NeuAc, N-acetyllactosamine, lactose, sialic acid, ST6N, ST3N
REFERENCE
Reference Id
REF-0000-000071
Issn
Print
Doi
10.1021/jo030042g
PubMed ID
12839452
Journal Name
The Journal of organic chemistry. (2003) 68 (14): 5602-13.
Article Title
Systematic syntheses and inhibitory activities of bisubstrate-type inhibitors of sialyltransferases.
Author
Hiroshi, Hinou; Xue-Long, Sun; Yukishige, Ito
Affiliation
RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
Reference Id
REF-0000-000072
Source
J. Org. Chem. 2003, 68, 5602-5613
Doi
10.1021/jo030042g

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)