Reaction:JCGG-RAC0001353

JCGG ID		JCGG-RAC0001353
Submitter		The Noguchi Institute
Reaction ID		R-0000-001353
Regist Date		2012/06/21 16:52:45
REACTANT
MOLECULE ID		JCGG-COM0001546 (Reaction Tree)
	Reactant Type	donor
	Mol	0.13 mmol
MOLECULE ID		JCGG-COM0001547 (Reaction Tree)
	Reactant Type	acceptor
	Mol	0.10 mmol
MOLECULE ID		JCGG-COM0000624
	Reactant Type	AgOTf
	Mol	0.26 mmol
MOLECULE ID		JCGG-COM0000047
	Reactant Type	Et3N
	Volume	0.5 mL
PRODUCT
MOLECULE ID		JCGG-COM0001548 (Reaction Tree)
	Product Type	alpha
	Yield	79%(alpha/beta=2.0/1)
MOLECULE ID		JCGG-COM0001549 (Reaction Tree)
	Product Type	beta
	Yield	79%(alpha/beta=2.0/1)
REACTION DETAIL
Reaction Time		16 hours, 30 minutes
Reaction Temp		room temp, NOT specified
Solvent		ClCH2CH2Cl, ClCH2CH2Cl
Comment		1) donor+acceptor, MS 3A, AgOTf, 2) +Et3N
		The donor, the acceptor, and MS 3A were mixed and stirred for 1 hour before the reaction.
COMMENT
Keywords: carbohydrates, glycosides, glycosylation, oligosaccharides, thioimidates
There are multiple phases in this reaction.
ATTENTION: There is a numerical discrepancy between the scheme and the written method. (the reaction time)
REFERENCE
Reference Id		REF-0000-000069
	Issn	Print
	Doi	10.1002/anie.200502694
	PubMed ID	16224750
	Journal Name	Angewandte Chemie (International ed. in English). (2005) 44 (43): 7123-6.
	Article Title	Development of an arming participating group for stereoselective glycosylation and chemoselective oligosaccharide synthesis.
	Author	James T, Smoot; Papapida, Pornsuriyasak; Alexei V, Demchenko
	Affiliation	Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA.
Reference Id		REF-0000-000070
	Source	Angew. Chem. Int. Ed. 2005, 44, 7123-7126
	Doi	10.1002/anie.200502694