JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0001270
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-001270
Regist Date
 2012/06/21 16:48:07
REACTANT
MOLECULE ID
 JCGG-COM0001418 (Reaction Tree)
Mol
 0.031 mmol
MOLECULE ID
 JCGG-COM0001424 (Reaction Tree)
Skeleton
JCGG-STR025718
Mol
 0.037 mmol
MOLECULE ID
 JCGG-COM0001377
Reactant Type
 KOtBu (1 M in THF)
Volume
 31 micro L
PRODUCT
MOLECULE ID
 JCGG-COM0001425 (Reaction Tree)
Yield
 70%
REACTION DETAIL
Reaction Time
 18 hours
Reaction Temp
 room temp
Solvent
 dry PhCH3
COMMENT
Keywords: galactal derivatives, 6-O-TIPS protection, trichloroacetimidates, Michael-type addition, 2-nitroglycals
REFERENCE
Reference Id
 REF-0000-000063
Issn
 Print
Doi
 10.1021/jo061670b
PubMed ID
 17503844
Journal Name
 The Journal of organic chemistry. (2007) 72 (12): 4367-77.
Article Title
 Glycal glycosylation and 2-nitroglycal concatenation, a powerful combination for mucin core structure synthesis.
Author
 Jürgen, Geiger; B Gopal, Reddy; Gottfried A, Winterfeld; R, Weber; M, Przybylski; R R, Schmidt
Affiliation
 Fachbereich Chemie, Universität Konstanz, Fach M 725, D - 78457 Konstanz, Germany.
Reference Id
 REF-0000-000064
Source
 J. Org. Chem. 2007, 72, 4367-4377
Doi
 10.1021/jo061670b
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)